对乙酰氨基酚中毒：肝损伤早期肝脏透析的病例报告
Acetaminophen Poisoning: Case Reports of Early Liver Dialysis for Hepatic Injury.
作者信息
Rahimi Mitra, Shadnia Shahin, Mostafazadeh Babak, Evini Peyman Erfan Talab, Hosseini Sayed Masoud, Deravi Niloofar, Belbasi Mohaddeseh
机构信息
Toxicological Research Center, Excellence Center of Clinical Toxicology, Department of Clinical Toxicology, Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences Tehran Iran.
Students Research Committee Shahid Beheshti University of Medical Sciences Tehran Iran.
出版信息
Clin Case Rep. 2025 Jul 17;13(7):e70642. doi: 10.1002/ccr3.70642. eCollection 2025 Jul.
In acetaminophen-induced acute liver failure, early use of extracorporeal artificial liver support using BS330/HA330-II filters improves liver function, coagulation profiles, bilirubin levels, and may obviate the need for liver transplantation. Early adjunctive use with N-acetylcysteine may optimize outcomes; further studies are necessary to confirm efficacy, safety, and standardized protocols.
在对乙酰氨基酚所致急性肝衰竭中，早期使用采用BS330/HA330-II滤器的体外人工肝支持可改善肝功能、凝血指标、胆红素水平，并可能避免肝移植的需要。早期与N-乙酰半胱氨酸联合使用可能使治疗效果最优化；有必要开展进一步研究以证实其疗效、安全性及标准化方案。
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