Zahabi Saeed, Salimibani Milad, Jóźwik Agnieszka, Asejczyk Magdalena
Department of Optics and Photonics, Wroclaw University of Science and Technology, Wroclaw, Poland.
Biomed Opt Express. 2025 May 6;16(6):2254-2274. doi: 10.1364/BOE.555315. eCollection 2025 Jun 1.
This study integrates mechanical and optical analyses to provide a robust framework for determining eye parameters and predicting visual changes under specific environmental or physical conditions. A 3D microstructural finite element model of the healthy human eye with elastic and viscoelastic properties was created and subjected to idealized and physiological intraocular pressure (IOP) load boundaries. It was our goal to investigate how the cornea, limbus, zonulas, and lens properties changed and how these changes affected key optical parameters such as focal length, Strehl ratio, and the RMS wave. The findings underscore the intricate role these factors play, highlight the significant role limbus play in preserving optimal visual function, and reveal biomechanical thresholds essential for maintaining ocular stability. A non-linear relationship was observed, in which moderate increases in stiffness of the limbus enhance stability while excessive stiffness compromises adaptability. This interdisciplinary approach advances our understanding of biomechanical and optical coupling, which is essential for vision optimization.
本研究整合了力学分析和光学分析，以提供一个强大的框架，用于确定眼睛参数并预测特定环境或身体条件下的视觉变化。创建了具有弹性和粘弹性特性的健康人眼三维微观结构有限元模型，并使其承受理想化和生理眼内压（IOP）负荷边界。我们的目标是研究角膜、角膜缘、悬韧带和晶状体特性如何变化，以及这些变化如何影响关键光学参数，如焦距、斯特列尔比和均方根波。研究结果强调了这些因素所起的复杂作用，突出了角膜缘在维持最佳视觉功能方面的重要作用，并揭示了维持眼球稳定性所必需的生物力学阈值。观察到一种非线性关系，即角膜缘刚度的适度增加可增强稳定性，而过度刚度则会损害适应性。这种跨学科方法推进了我们对生物力学和光学耦合的理解，这对视觉优化至关重要。
