Phrathep David, Billings Sabrina A, Khan Hamaad, Patel Palak, Mohseni Michael
Physical Medicine and Rehabilitation, Mayo Clinic, Jacksonville, USA.
Internal Medicine, Mayo Clinic, Jacksonville, USA.
Cureus. 2025 Jun 17;17(6):e86195. doi: 10.7759/cureus.86195. eCollection 2025 Jun.
Giant cell arteritis (GCA), also known as temporal arteritis, is a chronic inflammatory vasculitis that affects the large- and medium-sized arteries, which commonly includes the cranial branches of the carotid arteries. Manifestations range from constitutional symptoms, headache, and jaw claudication to transient or permanent monocular vision loss. Because its prognosis is poor if untreated, patients require prompt evaluation and appropriate treatment. We present an atypical case of binocular vision loss in a patient diagnosed with GCA with eosinophilic granulomatosis with polyangiitis. The patient declined a temporal artery biopsy and opted for ultrasonography, which helped clinch the ultimate diagnosis. His symptoms partially improved with high-dose steroids and tocilizumab in the hospital. Our case highlights the diagnostic challenges, appropriate specialist consultations required, and prompt management of GCA with overlapping vasculitis symptoms.
巨细胞动脉炎（GCA），也称为颞动脉炎，是一种慢性炎症性血管炎，累及大中型动脉，通常包括颈动脉的颅部分支。其表现范围从全身症状、头痛、颌部间歇性运动障碍到短暂或永久性单眼视力丧失。由于未经治疗预后较差，患者需要及时评估和适当治疗。我们报告一例诊断为GCA合并嗜酸性肉芽肿性多血管炎的患者出现双眼视力丧失的非典型病例。患者拒绝颞动脉活检，选择了超声检查，这有助于最终确诊。他在医院接受大剂量类固醇和托珠单抗治疗后症状部分改善。我们的病例强调了诊断挑战、所需的适当专科会诊以及对伴有重叠血管炎症状的GCA的及时管理。
