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Recipient-specific antibodies in HSCT: current knowledge and future perspectives.

作者信息

Pasi Annamaria, Prezioso Carmen Tania, Comoli Patrizia, Sbarsi Ilaria, Cacciatore Rosalia, Giorgiani Giovanna, Recupero Santina, Bergamaschi Paola, Torchio Margherita, Taurino Alessia, Losi Giulia, Zerbi Caterina, Bianchessi Antonio, Defrancesco Irene, Polverelli Nicola, Zecca Marco, Perotti Cesare Giuseppe

机构信息

Immunohematology and Transfusion Service, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Pediatric Hematology and Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

出版信息

Front Immunol. 2025 Jul 3;16:1621252. doi: 10.3389/fimmu.2025.1621252. eCollection 2025.

DOI:10.3389/fimmu.2025.1621252
PMID:40677722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12267003/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/12267003/9ad1ae4f77e7/fimmu-16-1621252-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/12267003/9ad1ae4f77e7/fimmu-16-1621252-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/12267003/9ad1ae4f77e7/fimmu-16-1621252-g001.jpg

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1
Recipient-specific antibodies in HSCT: current knowledge and future perspectives.造血干细胞移植中受者特异性抗体：当前认知与未来展望。
Front Immunol. 2025 Jul 3;16:1621252. doi: 10.3389/fimmu.2025.1621252. eCollection 2025.
2
[The impact of donor human leukocyte antigen-Bw4 allele on natural killer cell reconstitution and transplant-related mortality in haploidentical transplantation].[供者人类白细胞抗原-Bw4等位基因对单倍型移植中自然杀伤细胞重建及移植相关死亡率的影响]
Zhonghua Xue Ye Xue Za Zhi. 2024 May 14;45(5):453-461. doi: 10.3760/cma.j.cn.121090-20240314-00094.
3
Donor C1 Group KIR-ligand inferiority is linked to increased mortality in haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide.供体C1组KIR配体劣势与采用移植后环磷酰胺的单倍体造血干细胞移植中死亡率增加相关。
Cytotherapy. 2025 Apr;27(4):457-464. doi: 10.1016/j.jcyt.2024.12.003. Epub 2024 Dec 24.
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[Haploidentical hematopoietic stem cell transplantation: Guidelines from the Francophone society of marrow transplantation and cellular therapy (SFGM-TC)].[单倍型相合造血干细胞移植：法语国家骨髓移植与细胞治疗协会（SFGM-TC）指南]
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Combination treatment of rituximab and donor platelets infusion to reduce donor-specific anti-HLA antibodies for stem cells engraftment in haploidentical transplantation.利妥昔单抗联合供者血小板输注降低供者特异性抗 HLA 抗体以促进单倍体相合移植中干细胞植入。
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Donor-derived anti-HLA antibodies in a haploidentical hematopoietic cell transplant recipient shortly after transplant.移植后不久的单倍体造血细胞移植受者中供体来源的抗 HLA 抗体。
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[Impact of donor KIR2DS5 genotype on outcome following haploidentical hematopoietic stem cell transplantation].[供者KIR2DS5基因型对单倍体相合造血干细胞移植后结局的影响]
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[Effects of preexisting donor-specific HLA antibodies for graft failure in un-manipulated haploidentical hematopoietic stem cell transplantation].[预先存在的供者特异性HLA抗体对非预处理单倍体相合造血干细胞移植中移植物失败的影响]
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本文引用的文献

1
Incidence and Role of Recipient-Specific Antibodies in Allogeneic Hematopoietic Cell Transplantation from Mismatched Related Donors.非血缘相关供者异基因造血细胞移植中受者特异性抗体的发生率及作用
Transplant Cell Ther. 2024 Jan;30(1):99.e1-99.e10. doi: 10.1016/j.jtct.2023.10.015. Epub 2023 Oct 22.
2
Cytokine Release Syndrome and Associated Acute Toxicities in Pediatric Patients Undergoing Immune Effector Cell Therapy or Hematopoietic Cell Transplantation.接受免疫效应细胞治疗或造血细胞移植的儿科患者的细胞因子释放综合征及相关急性毒性
Front Oncol. 2022 Mar 24;12:841117. doi: 10.3389/fonc.2022.841117. eCollection 2022.
3
Endothelial Dysfunction after Hematopoietic Stem Cell Transplantation: A Review Based on Physiopathology.
造血干细胞移植后的内皮功能障碍：基于病理生理学的综述
J Clin Med. 2022 Jan 26;11(3):623. doi: 10.3390/jcm11030623.
4
The impact of HLA donor-specific antibodies on engraftment and the evolving desensitization strategies.HLA 供者特异性抗体对植入的影响和正在发展的脱敏策略。
Bone Marrow Transplant. 2022 Apr;57(4):526-531. doi: 10.1038/s41409-022-01578-w. Epub 2022 Jan 26.
5
Endothelial cell function and endothelial-related disorders following haematopoietic cell transplantation.造血细胞移植后内皮细胞功能及相关内皮紊乱。
Br J Haematol. 2020 Aug;190(4):508-519. doi: 10.1111/bjh.16621. Epub 2020 Apr 21.
6
Combination treatment of rituximab and donor platelets infusion to reduce donor-specific anti-HLA antibodies for stem cells engraftment in haploidentical transplantation.利妥昔单抗联合供者血小板输注降低供者特异性抗 HLA 抗体以促进单倍体相合移植中干细胞植入。
J Clin Lab Anal. 2020 Jul;34(7):e23261. doi: 10.1002/jcla.23261. Epub 2020 Feb 28.
7
Donor-specific anti-HLA antibodies and …recipient-specific anti-HLA antibodies? The conundrum on pregnancy in transplantation.供者特异性抗人白细胞抗原抗体与……受者特异性抗人白细胞抗原抗体？移植妊娠中的难题。
Am J Hematol. 2020 May;95(5):E128-E130. doi: 10.1002/ajh.25762. Epub 2020 Feb 29.
8
HLA antibodies in haematopoietic stem cell transplantation.HLA 抗体在造血干细胞移植中的作用。
HLA. 2019 Dec;94 Suppl 2:21-24. doi: 10.1111/tan.13741.
9
Who is the best donor for haploidentical stem cell transplantation?谁是单倍体造血干细胞移植的最佳供者？
Semin Hematol. 2019 Jul;56(3):194-200. doi: 10.1053/j.seminhematol.2018.08.003. Epub 2018 Aug 24.
10
Detecting donor-specific antibodies: the importance of sorting the wheat from the chaff.检测供体特异性抗体：区分优劣的重要性。
Hepatobiliary Surg Nutr. 2019 Feb;8(1):37-52. doi: 10.21037/hbsn.2019.01.01.