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利用新兴人工智能技术推进心脏运动估计以增强超声心动图图像配准

Advancing cardiac motion estimation with emerging AI techniques for enhanced echocardiographic image registration.

作者信息

Rajesh M, Balakrishnan S, Elankavi R

机构信息

Department of Computer Science and Engineering, Aarupadai Veedu Institute of Technology, Vinayaka Mission's Research Foundation (DU), Chennai, Tamil Nadu 603104, India.

出版信息

MethodsX. 2025 Jun 17;15:103432. doi: 10.1016/j.mex.2025.103432. eCollection 2025 Dec.

DOI:10.1016/j.mex.2025.103432
PMID:40678468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12268573/
Abstract

Monitoring and diagnosis of cardiovascular diseases rely on cardiac motion estimation. The methods used for registering echocardiographic images have drawbacks such as low resolution, noise, and distortion of the anatomy. In order to enhance the prediction of cardiac motion, this research presents an AI-powered architecture that makes use of Vision Transformers, Diffusion Models, and Neural Radiance Fields (NeRF). Adversarial and self-supervised contrastive learning enhance picture quality and generalisability across adult and foetal echocardiography, while a graph neural network (GNN)-based anatomical constraint maintains heart shape. Better, more accurate, more efficient real-time motion tracking without relying on massive labelled datasets is possible with the proposed approach. Cardiac motion analysis in a wide range of patient populations is now therapeutically viable, thanks to this innovative approach that improves echocardiographic picture registration.•Utilizes Vision Transformers, Diffusion Models, and NeRF for high-quality cardiac motion prediction.•Adversarial and self-supervised contrastive learning improve echocardiographic registration across demographics.•A GNN-based anatomical constraint ensures accurate heart morphology during motion analysis.

摘要

心血管疾病的监测和诊断依赖于心脏运动估计。用于配准超声心动图图像的方法存在诸如分辨率低、噪声和解剖结构失真等缺点。为了增强对心脏运动的预测,本研究提出了一种由人工智能驱动的架构,该架构利用视觉Transformer、扩散模型和神经辐射场(NeRF)。对抗性和自监督对比学习提高了图像质量以及在成人和胎儿超声心动图中的通用性,而基于图神经网络(GNN)的解剖学约束则保持心脏形状。所提出的方法能够在不依赖大量标记数据集的情况下实现更好、更准确、更高效的实时运动跟踪。由于这种改进超声心动图图像配准的创新方法,现在在广泛的患者群体中进行心脏运动分析在治疗上是可行的。

•利用视觉Transformer、扩散模型和NeRF进行高质量的心脏运动预测。

•对抗性和自监督对比学习改善了不同人群的超声心动图配准。

•基于GNN的解剖学约束可确保运动分析期间心脏形态的准确性。

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In-silico heart model phantom to validate cardiac strain imaging.用于验证心脏应变成像的计算机心脏模型体模。
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