Kloos H, McCullough F S
J Trop Med Hyg. 1985 Jun;88(3):189-96.
Using available information on the toxicity, phytochemistry, ethnomedical uses and geographic distribution of plants, potentially suitable species are identified for the control of intermediate hosts of schistosomiasis in Ethiopia's lowlands where endod (Phytolacca dodecandra) is not available. Of 46 species with moderate to high snail-killing potency, 35 are indigenous to Ethiopia. They include 12 plant species with molluscicidal levels similar to those of endod, four of which are particularly suitable for snail control because of their low mammalian toxicity. Another 127 species indigenous to Ethiopia belong to genera with proven molluscicidal activity. The model for plant screening used here permits preliminary assessment of the suitability of plant resources in a given region or locality for snail control programs using existing data, without prior testing of local plants, making this approach appropriate for many developing countries.
利用关于植物毒性、植物化学、民族医学用途及地理分布的现有信息，在埃塞俄比亚低地无法获取恩多德（商陆属十蕊商陆）的地区，确定了可能适合用于控制血吸虫病中间宿主的物种。在46种具有中度至高杀螺效力的物种中，有35种原产于埃塞俄比亚。其中包括12种杀软体动物活性水平与恩多德相似的植物物种，其中4种由于对哺乳动物毒性低而特别适合用于控制蜗牛。另外127种原产于埃塞俄比亚的物种属于已证实具有杀软体动物活性的属。这里使用的植物筛选模型允许利用现有数据对特定区域或地点的植物资源用于蜗牛控制项目的适宜性进行初步评估，而无需事先对当地植物进行测试，这使得该方法适用于许多发展中国家。
