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豚鼠后半规管阻塞对脑干听觉诱发电位的影响。

Effect on brainstem auditory evoked responses of posterior semicircular canal occlusion in guinea pigs.

作者信息

Parnes L S, McClure J A

出版信息

J Otolaryngol. 1985 Jun;14(3):145-50.

PMID:4068108
Abstract

The site of origin of benign paroxysmal positional vertigo is the posterior semicircular canal and when persistent, the condition is known as cupulolithiasis. Singular neurectomy is the current procedure of choice for the treatment of incapacitating cupulolithiasis. The neurectomy is difficult to learn and carries a significant risk of hearing loss. An alternative procedure, whereby the posterior canal is occluded, is discussed. This was performed on 11 guinea pigs and the effect on hearing was measured using brainstem evoked audiometry. Eight animals showed no hearing loss while the other three had a mild to moderate loss of hearing due to intra-operative complications. The effect of canal plugging on hearing compares favorably with the hearing results obtained with singular neurectomy. Posterior semicircular canal occlusion is suggested as a safer and technically easier treatment for incapacitating cupulolithiasis.

摘要

良性阵发性位置性眩晕的起源部位是后半规管,若病情持续存在,则称为嵴顶结石症。单孔神经切除术是目前治疗致残性嵴顶结石症的首选手术方法。该神经切除术难以掌握,且存在听力丧失的重大风险。本文讨论了一种替代手术方法,即闭塞后半规管。对11只豚鼠实施了该手术,并使用脑干诱发听力测定法测量其对听力的影响。8只动物未出现听力丧失,而另外3只因术中并发症出现了轻度至中度听力丧失。后半规管闭塞对听力的影响与单孔神经切除术的听力结果相比更具优势。对于致残性嵴顶结石症,建议采用后半规管闭塞术作为一种更安全且技术上更简便的治疗方法。

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