[后半规管瘘管豚鼠对多个同时刺激的听觉稳态反应及耳蜗形态分析]

[Analysis of auditory steady-state response to multiple simultaneous stimuli and cochlea morphology in guinea pigs with posterior semicircular canal fistula].

作者信息

Xie Nan-ping, Chen Guo-qiang, Yang Xing, Shu Si-yun

机构信息

Department of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.

出版信息

Nan Fang Yi Ke Da Xue Xue Bao. 2006 Apr;26(4):495-7.

PMID:16624763

Abstract

OBJECTIVE

To observe the changes of auditory steady-state response (ASSR) threshold in guinea pigs with posterior semicircular canal fistula.

METHODS

In 10 guinea pigs, a window was opened in the posterior semicircular canal of the left ear with the right ear serving as the control for testing the ASSR under anesthesia with pentobarbital sodium.

RESULTS

The mean and standard deviation of ASSR threshold (dB SPL) at 0.5, 1, 2, and 4 kHz in the left ear was 35.00+/-14.33, 25.50+/-12.37, 20.00+/-9.37 and 20.00+/-9.18, respectively, and was 31.00+/-16.19, 25.50+/-12.34, 18.00+/-6.96 and 18.50+/-6.71 in the right ear, respectively. Paired-sample t test showed no significant difference in the ASSR at the same frequency between the two ears.

CONCLUSION

Small fistula by surgery causes no significant hearing loss in guinea pigs.

摘要

目的

观察后半规管瘘管豚鼠听觉稳态反应（ASSR）阈值的变化。

方法

选取10只豚鼠，在戊巴比妥钠麻醉下，于左耳后半规管开一个窗口，以右耳作为对照来测试ASSR。

结果

左耳在0.5、1、2和4kHz时ASSR阈值（dB SPL）的均值和标准差分别为35.00±14.33、25.50±12.37、20.00±9.37和20.00±9.18，右耳分别为31.00±16.19、25.50±12.34、18.00±6.96和18.50±6.71。配对样本t检验显示双耳在相同频率下的ASSR无显著差异。