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肛门直肠畸形合并直肠会阴瘘患者的早期修复与延迟修复:对短期并发症及中期和长期肠道功能的影响

Early versus delayed repair in patients with anorectal malformation with rectoperineal fistula: impact on short-term complications and midterm and long-term bowel function.

作者信息

Xiao Xianming, Feng Wei, Xiang Chenzhu, Yuan Liang, Wang Zhili, Hou Jinping, Wang Yi

机构信息

Department of General and Neonatal Surgery, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China.

出版信息

Pediatr Surg Int. 2025 Jul 18;41(1):220. doi: 10.1007/s00383-025-06110-x.

DOI:10.1007/s00383-025-06110-x
PMID:40681952
Abstract

BACKGROUND

This study aims to investigate the impact of early versus delayed repair on early postoperative complications and midterm and long-term bowel function in ARM patients with rectoperineal fistula.

METHODS

A total of 568 ARM patients with rectoperineal fistula who underwent cutback anoplasty were identified at our hospital from 2015 to 2021. Early repair was defined as an anoplasty performed at or before 28 days of age. Delayed repair was defined as occurring after this period.

RESULTS

267 patients were finally enrolled, with 171 males and 96 females. 129 (48.3%) underwent early repair and 138 (51.7%) delayed repair. Early postoperative complication rates showed no significant difference between the two groups (0% vs. 0.7%, P = 1.000). No wound infections or dehiscence occurred in either group within 6 months postoperatively. The median Rintala score did not differ significantly between the early and delayed groups (20 vs. 20, P = 0.272). Based on the Krickenbeck classification, there were no significant differences between the groups regarding constipation, soiling, or voluntary bowel movements (P > 0.05).

CONCLUSIONS

Early and delayed repair have no significant impact on early postoperative complications and midterm and long-term bowel function in ARM patients with rectoperineal fistula. Neonatal cutback anoplasty is safe and effective for stable patients without major comorbidities, offering a favorable prognosis.

摘要

背景

本研究旨在探讨早期修复与延迟修复对患有直肠会阴瘘的肛门直肠畸形(ARM)患者术后早期并发症以及中期和长期肠道功能的影响。

方法

2015年至2021年期间,在我院共确定了568例接受后切肛门成形术的患有直肠会阴瘘的ARM患者。早期修复定义为在28日龄及之前进行的肛门成形术。延迟修复定义为在此时间段之后进行的手术。

结果

最终纳入267例患者,其中男性171例,女性96例。129例(48.3%)接受早期修复,138例(51.7%)接受延迟修复。两组术后早期并发症发生率无显著差异(0%对0.7%,P = 1.000)。术后6个月内两组均未发生伤口感染或裂开。早期组和延迟组的Rintala评分中位数无显著差异(20对20,P = 0.272)。根据Krickenbeck分类,两组在便秘、便污或自主排便方面无显著差异(P > 0.05)。

结论

早期修复和延迟修复对患有直肠会阴瘘的ARM患者术后早期并发症以及中期和长期肠道功能无显著影响。对于无重大合并症的稳定患者,新生儿后切肛门成形术安全有效,预后良好。

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本文引用的文献

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Br J Surg. 2024 Jan 31;111(2). doi: 10.1093/bjs/znae019.
2
Perioperative Histologically Controlled Fistula Resection in Patients with Imperforate Anus and Perineal Fistula.肛门闭锁合并会阴瘘患者的术中组织学控制瘘管切除。
Eur J Pediatr Surg. 2024 Oct;34(5):418-422. doi: 10.1055/s-0043-1777101. Epub 2023 Nov 28.
3
Bowel function and features of bowel dysfunction in preschool children with anorectal malformation type rectoperineal and rectovestibular fistula.
直肠肛门畸形直肠会阴型和直肠前庭瘘学龄前儿童的肠道功能和肠道功能障碍的特征。
Eur J Pediatr. 2024 Feb;183(2):599-610. doi: 10.1007/s00431-023-05306-4. Epub 2023 Nov 8.
4
Early postoperative feeding in single-stage repair of anorectal malformation with vestibular or perineal fistula is not associated with increased wound complications.一期前庭瘘或会阴瘘肛门直肠畸形修复术后早期喂养与增加伤口并发症无关。
J Pediatr Surg. 2023 Mar;58(3):467-470. doi: 10.1016/j.jpedsurg.2022.07.009. Epub 2022 Jul 14.
5
The cutback revisited - The posterior rectal advancement anoplasty for certain anorectal malformations with rectoperineal fistula.再次回顾缩窄术 - 经肛门后直肠推进皮瓣成形术治疗某些伴有直肠会阴瘘的肛门直肠畸形。
J Pediatr Surg. 2022 Sep;57(9):85-88. doi: 10.1016/j.jpedsurg.2021.12.014. Epub 2021 Dec 17.
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Pediatr Surg Int. 2022 Feb;38(2):337-343. doi: 10.1007/s00383-021-05035-5. Epub 2021 Oct 27.
7
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