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干燥综合征肺囊肿的研究综述

Review of research on pulmonary cysts in sjögren's syndrome.

作者信息

Pan Cai-Hong, Zhang Xu-Fei, Chen Chen, An Xiao-Bei

机构信息

Department of Rheumatology and Immunology, The Third Hospital of Shijiazhuang, No. 15 South Sports Street, Chang'an district, Shijiazhuang, 050000, China.

出版信息

J Cardiothorac Surg. 2025 Jul 18;20(1):306. doi: 10.1186/s13019-025-03540-5.

Abstract

Sjögren's syndrome (SS) is a chronic systemic autoimmune disease mainly involving exocrine glands and particularly affecting the salivary glands and lacrimal glands, thus inducing a dry mouth and dry eyes. Extraglandular organs are also involved in SS, and this results in damage to multiple systems. Among these, lung damage is more common, with high morbidity and mortality rates, and the lack of typical symptoms in the early stages makes it challenging to identify it. The main pulmonary manifestations of SS are bronchitis, pulmonary hypertension, pulmonary cysts, pulmonary amyloidosis, interstitial pneumonia, and pulmonary fibrosis. Cystic lung disease affects about 4-46.2% of patients with SS. The imaging characteristics of pulmonary cysts in SS, including the size, number, morphology, and distribution, as well as differential diagnosis, mechanisms underlying the formation of pulmonary cysts, and current treatment strategies, are presented in this review.

摘要

干燥综合征(SS)是一种慢性全身性自身免疫性疾病,主要累及外分泌腺,尤其影响唾液腺和泪腺,从而导致口干和眼干。腺外器官也参与SS发病,这会导致多系统损害。其中,肺部损害较为常见,发病率和死亡率较高,且早期缺乏典型症状,难以识别。SS的主要肺部表现为支气管炎、肺动脉高压、肺囊肿、肺淀粉样变性、间质性肺炎和肺纤维化。肺囊性疾病在约4% - 46.2%的SS患者中出现。本文综述了SS中肺囊肿的影像学特征,包括大小、数量、形态和分布,以及鉴别诊断、肺囊肿形成的机制和当前的治疗策略。

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