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恒河猴(猕猴)软腭富含肌上皮细胞的多形性腺瘤

Myoepithelial-rich pleomorphic adenoma of the soft palate in a rhesus monkey (Macaca mulatta).

作者信息

Starost Matthew F, King Christopher, Vaughan Kelli L, Mattison Julie A

机构信息

Office of Research Services, Division of Veterinary Resources, National Institutes of Health, Building 28A, Bethesda, Maryland 20892, USA.

Office of Research Services, Division of Veterinary Resources, National Institutes of Health, Building 28A, Bethesda, Maryland 20892, USA.

出版信息

J Comp Pathol. 2025 Jul 17;221:14-18. doi: 10.1016/j.jcpa.2025.07.001.

Abstract

A 39-year-old female rhesus macaque (Macaca mulatta) presented for stertor that had progressed over a 2-year period. A mass involving the soft palate was seen partially obstructing the oropharynx. Histopathological examination revealed a well-circumscribed, partially encapsulated mass composed primarily of myoepithelial cells with scattered duct-like structures, squamous metaplasia and hyaline stroma. The mass was diagnosed as a myoepithelial-rich pleomorphic adenoma. To the best of our knowledge, this is the first reported case in non-human primates.

摘要

一只39岁的雌性恒河猴(猕猴属)因持续了两年的鼾症前来就诊。发现一个累及软腭的肿物部分阻塞口咽。组织病理学检查显示一个边界清楚、部分包膜完整的肿物,主要由肌上皮细胞组成,伴有散在的导管样结构、鳞状化生和透明质基质。该肿物被诊断为富含肌上皮的多形性腺瘤。据我们所知,这是首例在非人灵长类动物中报道的病例。

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