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近红外光谱技术用于评估早产儿肾脏氧合情况:肾脏位置、深度及左右侧差异

Evaluation of kidney oxygenation monitoring with near infrared spectroscopy in preterm neonates: kidney location, depth, and laterality differences.

作者信息

Harer Matthew W, Walker Kate, Gadek Lauren, Schwingle Shayla, Nelson Cassandra, Baker Meg, Alfaro Elena, Bauer Adam S, Condit Paige

机构信息

Division of Neonatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

University of Wisconsin-Madison, Madison, WI, USA.

出版信息

J Perinatol. 2025 Jul 19. doi: 10.1038/s41372-025-02358-2.

DOI:10.1038/s41372-025-02358-2
PMID:40683986
Abstract

INTRODUCTION

Near infrared spectroscopy (NIRS) monitoring of preterm kidney oxygenation is increasing. We sought to evaluate kidney positioning and oxygenation differences between the right and left kidneys.

METHODS

Preterm neonates <32 weeks' gestational age were enrolled in a prospective observational NIRS study. Two three-hour epochs of simultaneous bilateral kidney monitoring were performed (5-8 days, 9-14 days). Point of care kidney ultrasound was performed once between days 5 and 12.

RESULTS

There were no right-left differences in skin to superior kidney depth (0.39 and 0.38 cm; p = 0.62) or spine to kidney distance (1.06 and 1.02 cm; p = 0.31). There was a difference in right-left skin to inferior kidney depth (2.15 and 2.04 cm; p = 0.02). There was higher oxygenation in the left kidney compared to the right (65.6 vs. 62.7%, p < 0.01). Hourly individual differences of >10% were seen in 37% of neonates.

CONCLUSIONS

Differences in kidney depth and right-left oxygenation exist in preterm neonates.

摘要

引言

近红外光谱(NIRS)对早产儿肾脏氧合的监测正在增加。我们试图评估左右肾脏的位置及氧合差异。

方法

孕周<32周的早产儿被纳入一项前瞻性观察性NIRS研究。进行了两个为期三小时的双侧肾脏同步监测时段(出生后5 - 8天、9 - 14天)。在第5天至第12天之间进行了一次床旁肾脏超声检查。

结果

皮肤至肾脏上极深度(0.39和0.38厘米;p = 0.62)或脊柱至肾脏距离(1.06和1.02厘米;p = 0.31)不存在左右差异。皮肤至肾脏下极深度存在左右差异(2.15和2.04厘米;p = 0.02)。左肾氧合高于右肾(65.6%对62.7%,p < 0.01)。37%的新生儿每小时个体差异>10%。

结论

早产儿存在肾脏深度及左右氧合差异。

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