Khajeh Fatemeh, Zeighami Shahryar, Ariafar Ali, Bazargani Zahra, Hakimelahi Hossein
Pathology Department, Fasa University of Medical Sciences, Urology Department, Iran.
Urology Department, Shiraz University of Medical Sciences, Iran.
Urol Case Rep. 2025 Jul 1;62:103108. doi: 10.1016/j.eucr.2025.103108. eCollection 2025 Sep.
Renal angiomyolipomas (AMLs) are benign tumors that can mimic renal cell carcinoma (RCC) when fat content is minimal. We report a 56-year-old male with recurrent paralysis and hypokalemia, presumed to be a paraneoplastic syndrome of RCC, prompting radical nephrectomy. Histopathology and immunohistochemistry (IHC) revealed an 8 cm AML, and hypokalemia resolved post-surgery. This case underscores the diagnostic challenge of minimal-fat AMLs and suggests that an accurate preoperative diagnosis could have enabled kidney-sparing surgery.
肾血管平滑肌脂肪瘤（AMLs）是一种良性肿瘤，当脂肪含量极少时，可能会被误诊为肾细胞癌（RCC）。我们报告了一名56岁男性，患有复发性麻痹和低钾血症，推测为RCC的副肿瘤综合征，因此接受了根治性肾切除术。组织病理学和免疫组化（IHC）检查显示为一个8厘米的AML，术后低钾血症得到缓解。该病例凸显了低脂肪AMLs的诊断挑战，并表明准确的术前诊断本可使保留肾脏的手术成为可能。
