一名孕妇的非肌层浸润性膀胱癌
Non-muscle invasive bladder cancer in a pregnant patient.
作者信息
van Jaarsveld Návan, John Jeff
机构信息
Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London, 5200, South Africa.
Division of Urology, Department of Surgery, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa.
出版信息
Urol Case Rep. 2025 Jul 4;62:103119. doi: 10.1016/j.eucr.2025.103119. eCollection 2025 Sep.
Malignant bladder tumors during pregnancy are exceedingly rare and account for less than 2.5 % of all malignancies. NMIBC presents unique diagnostic and management challenges, particularly in balancing maternal and fetal outcomes. We describe a 29-year-old woman diagnosed with NMIBC at 10 weeks' gestation, presenting with macroscopic hematuria. Ultrasonography and MRI confirmed the diagnosis, and TURBT revealed a high-grade T1 NMIBC. Post-operative surveillance and deferred intravesical therapy ensured maternal and fetal safety. The case underscores the challenges in balancing oncological and obstetric outcomes. While TURBT is safe during pregnancy, comprehensive follow-up and post-partum BCG are critical for long-term disease control.
妊娠期恶性膀胱肿瘤极为罕见，占所有恶性肿瘤的比例不到2.5%。非肌层浸润性膀胱癌（NMIBC）带来了独特的诊断和管理挑战，尤其是在平衡母婴结局方面。我们描述了一名29岁女性，在妊娠10周时被诊断为NMIBC，表现为肉眼血尿。超声检查和磁共振成像（MRI）确诊了病情，经尿道膀胱肿瘤电切术（TURBT）显示为高级别T1期NMIBC。术后监测和延迟膀胱内灌注治疗确保了母婴安全。该病例凸显了在平衡肿瘤学和产科结局方面的挑战。虽然TURBT在孕期是安全的，但全面的随访和产后卡介苗灌注治疗对于长期疾病控制至关重要。
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