Mi Yan, Wang Jing
Department of Endocrinology, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, Hubei, China.
Front Endocrinol (Lausanne). 2025 Jul 4;16:1612047. doi: 10.3389/fendo.2025.1612047. eCollection 2025.
Diabetic foot ulcers (DFUs), a common complication of diabetes, are often accompanied by delayed wound healing, pain, psychological distress, and sleep disturbances.
To evaluate the effectiveness of personalized continuous care (PCC) compared to routine care in improving wound healing, symptom severity, and psychological/sleep outcomes in DFU patients.
A retrospective cohort study of 60 DFU patients (2021-2024) compared PCC (n=30) with routine care (n=30). Outcomes assessed included wound area reduction, granulation tissue coverage, symptom scores (ulceration, necrosis, pain), and validated psychological (SDS, SAS) and sleep (AIS) scales.
The PCC group showed superior wound healing (40.51% . 27.43% area reduction; 61.66% . 46.32% granulation coverage, p<0.05), lower symptom scores (ulceration: 3.18 ± 0.45 . 4.46 ± 0.6; pain: 2.01 ± 0.29 . 3.45 ± 0.58, p<0.01), and improved psychological (SDS: 32.1 ± 3.88 . 44.87 ± 4.05; SAS: 30.36 ± 3.77 . 43.25 ± 4.56, p<0.001) and sleep outcomes (AIS: 8.23 ± 0.6 . 11.33 ± 0.94, p<0.001).
PCC enhances DFU wound healing, alleviates symptoms, and improves psychological well-being and sleep quality, supporting its integration routine clinical practice.
糖尿病足溃疡(DFU)是糖尿病的常见并发症,常伴有伤口愈合延迟、疼痛、心理困扰和睡眠障碍。
评估个性化持续护理(PCC)与常规护理相比,在改善DFU患者伤口愈合、症状严重程度以及心理/睡眠结局方面的有效性。
一项对60例DFU患者(2021 - 2024年)的回顾性队列研究,将PCC组(n = 30)与常规护理组(n = 30)进行比较。评估的结局包括伤口面积缩小、肉芽组织覆盖情况、症状评分(溃疡、坏死、疼痛)以及经过验证的心理量表(SDS、SAS)和睡眠量表(AIS)。
PCC组显示出更好的伤口愈合效果(伤口面积缩小40.51% > 27.43%;肉芽组织覆盖61.66% > 46.32%,p < 0.05),更低的症状评分(溃疡:3.18 ± 0.45 < 4.46 ± 0.6;疼痛:2.01 ± 0.29 < 3.45 ± 0.58,p < 0.01),以及改善的心理结局(SDS:32.1 ± 3.88 < 44.87 ± 4.05;SAS:30.36 ± 3.77 < 43.25 ± 4.56,p < 0.001)和睡眠结局(AIS:8.23 ± 0.6 < 11.33 ± 0.94,p < 0.001)。
PCC可促进DFU伤口愈合,减轻症状,改善心理健康和睡眠质量,支持将其纳入常规临床实践。