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Bone marrow mesenchymal stroma cell serves as a harbor anchoring acute B lymphoblastic leukemia cells.

作者信息

Wu Kunpeng, Wang Fen, Shen Min, Liang Xiaohui, Wei Dan, Zhu Xi, Qu Ying, Wei Xunbin, Jiang Hua, Chen Tong

机构信息

Department of Hematology, Huashan Hospital, Fudan University, Shanghai 200040, China.

Center of Precision Medicine for Blood Diseases, Fudan University, Shanghai 200040, China.

出版信息

Genes Dis. 2025 Apr 12;12(6):101637. doi: 10.1016/j.gendis.2025.101637. eCollection 2025 Nov.

DOI:10.1016/j.gendis.2025.101637
PMID:40687610
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12270788/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d212/12270788/db847c594ed3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d212/12270788/db847c594ed3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d212/12270788/db847c594ed3/gr1.jpg

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本文引用的文献

1
Dysregulated stem cell niches and altered lymphocyte recirculation cause B and T cell lymphopenia in WHIM syndrome.异常调控的干细胞龛和改变的淋巴细胞再循环导致 WHIM 综合征中 B 和 T 细胞减少。
Sci Immunol. 2022 Sep 23;7(75):eabo3170. doi: 10.1126/sciimmunol.abo3170.
2
Mesenchymal stem cell-derived exosomes in cancer therapy resistance: recent advances and therapeutic potential.间质干细胞衍生的外泌体在癌症治疗耐药中的作用：最新进展和治疗潜力。
Mol Cancer. 2022 Sep 13;21(1):179. doi: 10.1186/s12943-022-01650-5.
3
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress.
激活的基质细胞转移线粒体以挽救急性淋巴细胞白血病细胞免受氧化应激。
Blood. 2019 Oct 24;134(17):1415-1429. doi: 10.1182/blood.2019001398.
4
Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells.细胞黏附介导的线粒体转移有助于间充质干细胞诱导 T 细胞急性淋巴细胞白血病细胞的化疗耐药性。
J Hematol Oncol. 2018 Jan 22;11(1):11. doi: 10.1186/s13045-018-0554-z.
5
Human bone marrow-derived mesenchymal stem cell gene expression patterns vary with culture conditions.人骨髓间充质干细胞的基因表达模式随培养条件而变化。
Blood Res. 2013 Jun;48(2):107-14. doi: 10.5045/br.2013.48.2.107. Epub 2013 Jun 25.