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The effect of sodium-glucose cotransporter 2 inhibition mediated by blood metabolites in lymphocytic leukemia.

作者信息

Wen Diguang, Lei Kai, Ma Xiang, Deng Jianchuan

机构信息

Department of Hematology, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.

Hepatobiliary Surgery Department, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.

出版信息

Genes Dis. 2025 May 2;12(6):101664. doi: 10.1016/j.gendis.2025.101664. eCollection 2025 Nov.

DOI:10.1016/j.gendis.2025.101664
PMID:40687613
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12270927/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a5b/12270927/b364dc21cdca/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a5b/12270927/b364dc21cdca/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a5b/12270927/b364dc21cdca/gr1.jpg

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本文引用的文献

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Diabetes Obes Metab. 2024 Nov;26(11):5336-5346. doi: 10.1111/dom.15895. Epub 2024 Sep 2.
2
SGLT2 inhibition, circulating metabolites, and atrial fibrillation: a Mendelian randomization study.SGLT2 抑制作用、循环代谢物与心房颤动：一项孟德尔随机研究。
Cardiovasc Diabetol. 2023 Oct 17;22(1):278. doi: 10.1186/s12933-023-02019-8.
3
Structural repurposing of SGLT2 inhibitor empagliflozin for strengthening anti-heart failure activity with lower glycosuria.
钠-葡萄糖协同转运蛋白2（SGLT2）抑制剂恩格列净的结构优化以增强抗心力衰竭活性并降低糖尿
Acta Pharm Sin B. 2023 Apr;13(4):1671-1685. doi: 10.1016/j.apsb.2022.08.023. Epub 2022 Sep 5.
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Impact of anti-diabetic sodium-glucose cotransporter 2 inhibitors on tumor growth of intractable hematological malignancy in humans.
Biomed Pharmacother. 2022 May;149:112864. doi: 10.1016/j.biopha.2022.112864. Epub 2022 Mar 31.
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Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus: Cardiovascular and Kidney Effects, Potential Mechanisms, and Clinical Applications.钠-葡萄糖协同转运蛋白2抑制剂在糖尿病治疗中的应用：心血管和肾脏效应、潜在机制及临床应用
Circulation. 2016 Sep 6;134(10):752-72. doi: 10.1161/CIRCULATIONAHA.116.021887. Epub 2016 Jul 28.