Siyiti Sikandaer, Hang Lin, Siyiti Adila, Jiangtao Sui
Spinal Surgery, Sixth Afliated Hospital of Xinjiang Medical University, Xinjiang, China.
The Sixth Clinical Medical College, Xinjiang Medical University, Xinjiang, China.
Front Med (Lausanne). 2025 Jul 4;12:1573347. doi: 10.3389/fmed.2025.1573347. eCollection 2025.
This study aims to evaluate the clinical effectiveness of minimally invasive versus conventional open posterior methods for the excision of brucellosis lesions in the context of spondylitis treatment. The findings are intended to inform and guide clinical practice.
Forty-three patients with brucellosis spondylitis who attended our hospital from January 2020 to June 2023 were selected and divided into minimally invasive endoscopic brucellosis lesion removal (group A) = 18 and traditional open lesion removal group (group B) = 25 according to the operation type. All patients were given antibiotic treatment before operation. Analyze the relevant clinical indicators.
① There were no statistically significant differences ( > 0.05) between the two groups in terms of age, gender, body mass index (BMI), medical history, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), procalcitonin (PCT), D-dimer, hemoglobin (Hb), visual analog scale (VAS) score, Oswestry Disability Index (ODI) score and recurrence rate. ② The operation time ( < 0.012), intraoperative blood loss ( < 0.012), and postoperative hospital stay ( < 0.012) in group A were significantly shorter than those in group B, and the differences between the two groups were statistically significant ( < 0.05). No significant differences were observed in the remaining outcome measures.
The results of this study showed that minimally invasive endoscopic brucellosis lesion removal could achieve the same efficacy as compared with traditional open posterior lesion removal, but minimally invasive surgery has the advantages of shorter operative time, lower intraoperative hemorrhage and more obvious advantages in postoperative rehabilitation, etc., which makes it clinically feasible and effective procedure.
本研究旨在评估在脊柱炎治疗背景下，微创与传统开放后路方法切除布鲁氏菌病病灶的临床疗效。研究结果旨在为临床实践提供信息和指导。
选取2020年1月至2023年6月在我院就诊的43例布鲁氏菌病脊柱炎患者，根据手术方式分为微创内镜下布鲁氏菌病病灶清除组（A组，18例）和传统开放病灶清除组（B组，25例）。所有患者术前均给予抗生素治疗。分析相关临床指标。
①两组在年龄、性别、体重指数（BMI）、病史、红细胞沉降率（ESR）、C反应蛋白（CRP）、降钙素原（PCT）、D-二聚体、血红蛋白（Hb）、视觉模拟评分法（VAS）评分、Oswestry功能障碍指数（ODI）评分及复发率方面，差异均无统计学意义（>0.05）。②A组手术时间（<0.012）、术中出血量（<0.012）及术后住院时间（<0.012）均明显短于B组，两组差异有统计学意义（<0.05）。其余观察指标差异无统计学意义。
本研究结果表明，微创内镜下布鲁氏菌病病灶清除术与传统开放后路病灶清除术疗效相当，但微创手术具有手术时间短、术中出血少、术后康复优势更明显等优点，是一种临床可行且有效的手术方式。
