Dalu Davide, Iardino Rosaria, Vaccher Emanuela, Lasagna Angioletta, Digaetano Margherita, Leone Alberto Giovanni, Ruggieri Lorenzo, Massari Eva, Blondeaux Eva, Gori Andrea, Mussini Cristina, Rizzardini Giuliano, Bassetti Matteo, Di Biagio Antonio, Mastroianni Claudio M, Brogonzoli Luisa, Cascio Mario, Perrone Francesco, Cinieri Saverio, Beretta Giordano D, La Verde Nicla
Department of Oncology, Luigi Sacco University Hospital, ASST Fatebenefratelli Sacco, Milan, Italy.
The Bridge Foundation, Milan, Italy.
HIV AIDS (Auckl). 2025 Jul 15;17:215-226. doi: 10.2147/HIV.S519956. eCollection 2025.
Since the mid-1990s, the adoption of combined antiretroviral therapy (cART) has significantly reduced HIV-related mortality and morbidity. Nevertheless, cancer continues to be the leading cause of death in people living with HIV (PLWH). We conducted a survey to assess the knowledge and inter-disciplinarity among the Italian oncologists and infectious disease specialists in the cancer prevention and treatment of PLWH.
All the members of AIOM, SIMIT and SITA who are oncologists and infectious disease specialists were invited via email. A survey with 24 queries was administered using a web-based platform. Data were analysed with the chi-square or Fisher exact tests to explore any significant difference between the two specialist subgroups.
From April to June 2023, 182 participants filled in the questionnaires. A low rate of respondents from each scientific society was reported (3% for AIOM, 8% from SIMIT and 2% from SITA). All interviewees agreed that HIV infection was a relevant risk factor for cancer (95.1%) and that PLWH had limited access to clinical trials (73.1%). More than a third of oncologists worked in a hospital without an infectious diseases department, using a remote method of communication for interdisciplinary discussion (telephone and Email were used in 64.5% of cases). Eighty-four percent of the oncologists vs 51.4% of the infectious disease specialists had in charge less than 5 patients with HIV during the previous year.
The results of this survey underscore the opportunity for education, interdisciplinary collaboration, and organizational support to optimize cancer care for PLWH. A Hub&Spoke model could represent a potential facilitation to build-up in the near future through inter-societal collaboration.
自20世纪90年代中期以来，联合抗逆转录病毒疗法（cART）的采用显著降低了与艾滋病相关的死亡率和发病率。然而，癌症仍然是艾滋病感染者（PLWH）的主要死因。我们进行了一项调查，以评估意大利肿瘤学家和传染病专家在PLWH癌症预防和治疗方面的知识及跨学科情况。
通过电子邮件邀请了意大利肿瘤医学协会（AIOM）、意大利传染病学会（SIMIT）和意大利肿瘤内科医生协会（SITA）中所有的肿瘤学家和传染病专家。使用基于网络的平台进行了一项包含24个问题的调查。采用卡方检验或费舍尔精确检验对数据进行分析，以探讨两个专家亚组之间的任何显著差异。
2023年4月至6月，182名参与者填写了问卷。每个科学协会的受访者比例较低（AIOM为3%，SIMIT为8%，SITA为2%）。所有受访者都认为艾滋病毒感染是癌症的一个相关危险因素（95.1%），并且PLWH参与临床试验的机会有限（73.1%）。超过三分之一的肿瘤学家在没有传染病科的医院工作，使用远程沟通方式进行跨学科讨论（64.5%的情况使用电话和电子邮件）。在前一年，84%的肿瘤学家负责的艾滋病毒感染者少于5名，而传染病专家这一比例为51.4%。
本次调查结果强调了开展教育、跨学科合作以及提供组织支持以优化PLWH癌症护理的机会。在不久的将来，通过跨学会合作，中心辐射模式可能是一种潜在的促进方式。
