Chen Wushu, Li Xingpei, Mai Junye, Tang Kailang, Wang Yingqiao, Lu Yan-Yan, Liang Jie, Li Ni-Jiao, Qin Xiu-Yu, Li Yu, Yao Lunkai, Qiu Ye
Guangzhou Medical University, China.
Department of Gastroenterology and Respiratory Medicine, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
J Transl Autoimmun. 2025 Jun 27;11:100297. doi: 10.1016/j.jtauto.2025.100297. eCollection 2025 Dec.
At present, there is a lack of detailed understanding and research on the pathogenesis and treatment of Hyperimmunoglobulin M syndrome (HIGM), Hyperimmunoglobulin E syndrome (HIES), and hyperimmunoglobulin D syndrome (HIDS), and few studies have been conducted to correlate the pathogenesis and treatment of the three disorders. The existing studies are rarely related to the three diseases. We searched PubMed for a large number of relevant literature and analyzed and summarized the contents. We analyzed and introduced the three diseases and their Categorization, Epidemiology, Clinical manifestations, Laboratory diagnosis, and Treatment by means of tables and Figures. It is hoped that this analysis and summary can play a certain role in the research and treatment of related diseases and promote the understanding and prevention of related diseases.
目前，对于高免疫球蛋白M综合征（HIGM）、高免疫球蛋白E综合征（HIES）和高免疫球蛋白D综合征（HIDS）的发病机制及治疗缺乏详细的了解和研究，很少有研究将这三种疾病的发病机制和治疗联系起来。现有的研究很少涉及这三种疾病。我们在PubMed上搜索了大量相关文献，并对其内容进行了分析和总结。我们通过表格和图表分析并介绍了这三种疾病及其分类、流行病学、临床表现、实验室诊断和治疗。希望这种分析和总结能在相关疾病的研究和治疗中发挥一定作用，促进对相关疾病的认识和预防。
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