Wong Walter-Soon-Yaw, Koh Hun Yi, Lee Kong Hwee, Bin Abd Razak Hamid Rahmatullah
Orthopaedic Surgery, Sengkang General Hospital, Singapore, SGP.
Orthopaedic Surgery, Singapore General Hospital, Singapore, SGP.
Cureus. 2025 Jun 18;17(6):e86272. doi: 10.7759/cureus.86272. eCollection 2025 Jun.
Medial opening wedge high tibial osteotomy (MOWHTO) is a highly common procedure for correcting varus malalignment of the knee. The current gold standard for filling this osteotomy gap is autologous bone graft, which is associated with donor site morbidity. Allograft bone graft is also an alternative; however, it is associated with certain disadvantages, such as storage cost, limited supply, and the risk of infection transmission. Consequently, there has been a growing interest in and further developments of synthetic options for filling the osteotomy gap. We would like to introduce and describe the process of manufacturing and utilizing the novel Osteopore® 3D-printed, honeycomb-structured, polycaprolactone and β-tricalcium phosphate (PCL-TCP) synthetic bone wedge for filling the gap in MOWHTO. This study will also include illustrations of postoperative radiographs and CT scans to showcase bony remodeling over a period of up to 12 months. In the era of additive manufacturing and the pursuit of more biocompatible materials, the use of a patient-specific 3D-printed, honeycomb-structured, PCL-TCP bone spacer wedge in MOWHTO is promising and may serve as a viable alternative to autograft and allograft bone grafts. It offers the potential to maintain biomechanical stability and facilitate the healing of the osteotomy gap without the associated drawbacks of bone graft.
内侧开口楔形高位胫骨截骨术(MOWHTO)是一种用于矫正膝关节内翻畸形的常见手术。目前填充该截骨间隙的金标准是自体骨移植,但这会带来供区并发症。同种异体骨移植也是一种选择;然而,它存在一些缺点,如储存成本、供应有限以及感染传播风险。因此,人们对用于填充截骨间隙的合成材料的兴趣日益浓厚,并对其进行了进一步开发。我们想介绍并描述新型Osteopore® 3D打印蜂窝结构聚己内酯和β-磷酸三钙(PCL-TCP)合成骨楔的制造和使用过程,该骨楔用于填充MOWHTO中的间隙。本研究还将包括术后X线片和CT扫描图像,以展示长达12个月的骨重塑情况。在增材制造时代以及对更具生物相容性材料的追求中,在MOWHTO中使用患者定制的3D打印蜂窝结构PCL-TCP骨间隔楔是有前景且可行的,可替代自体骨移植和同种异体骨移植。它有可能维持生物力学稳定性并促进截骨间隙愈合,同时避免骨移植的相关缺点。