Ha Duong Dai, Toan Vo Thanh, Tung Le Ba
Department of Surgery, Hanoi Medical University, Hanoi, Vietnam.
Neurosurgery Center, Viet Duc Hospital, Hanoi, Vietnam.
Med Arch. 2025;79(2):142-146. doi: 10.5455/medarh.2025.79.142_146.
Traumatic brain injury (TBI) is one of the leading causes of death and severe neurological sequelae worldwide, profoundly impacting patients' quality of life and imposing a significant economic and social burden. Numerous studies have shown that the mortality and neurological disability rates following TBI remain high, with over 20% of patients either dying or suffering severe disability.
This study aims to assess the outcomes of decompressive craniectomy (DC) in patients with severe traumatic brain injury (TBI) at discharge and 3 months postoperatively, while identifying prognostic factors influencing patient outcomes during this period.
A prospective descriptive study was conducted on all patients with severe TBI indicated for DC from March to December 2024 at Viet Duc University Hospital. CT scan characteristics were evaluated using the Rotterdam and Helsinki scoring systems. Clinical outcomes were assessed using the Glasgow Outcome Scale (GOS) at discharge and 3 months post-injury. Prognostic factors were analyzed through multivariate logistic regression and receiver operating characteristic (ROC) curve analysis.
Among 150 patients with severe TBI who underwent DC, 71.33% had poor outcomes (GOS 1-2-3) at discharge. This proportion decreased to 40.85% after 3 months, indicating notable recovery. Poor outcomes at discharge were significantly associated with advanced age, high Helsinki score on admission, and presence of hemiparesis. These factors also demonstrated stronger predictive power at the 3-month follow-up. The Rotterdam score correlated with discharge outcomes and was valuable for early risk stratification, whereas the Helsinki score was predictive at both discharge and follow-up time points.
Decompressive craniectomy is an effective life-saving procedure in patients with severe TBI. However, surgical decision-making should be guided by comprehensive prognostic evaluation, including age, neurological status at admission, and radiological scoring systems. Such multifactorial assessment enhances the likelihood of survival, meaningful functional recovery, and long-term quality of life.
创伤性脑损伤(TBI)是全球范围内导致死亡和严重神经后遗症的主要原因之一,深刻影响患者的生活质量,并带来巨大的经济和社会负担。大量研究表明,TBI后的死亡率和神经残疾率仍然很高,超过20%的患者死亡或遭受严重残疾。
本研究旨在评估重度创伤性脑损伤(TBI)患者行减压性颅骨切除术(DC)后出院时及术后3个月的预后,同时确定在此期间影响患者预后的预测因素。
对2024年3月至12月在越南德医院所有因DC而接受治疗的重度TBI患者进行前瞻性描述性研究。使用鹿特丹和赫尔辛基评分系统评估CT扫描特征。在出院时和受伤后3个月使用格拉斯哥预后量表(GOS)评估临床结果。通过多因素逻辑回归和受试者操作特征(ROC)曲线分析来分析预测因素。
在150例行DC的重度TBI患者中,71.33%在出院时预后不良(GOS 1-2-3)。3个月后这一比例降至40.85%,表明有显著恢复。出院时预后不良与高龄、入院时赫尔辛基评分高以及偏瘫的存在显著相关。这些因素在3个月随访时也显示出更强的预测能力。鹿特丹评分与出院结果相关,对早期风险分层有价值,而赫尔辛基评分在出院和随访时间点均具有预测性。
减压性颅骨切除术是重度TBI患者有效的挽救生命的手术。然而,手术决策应以全面的预后评估为指导,包括年龄、入院时的神经状态和放射学评分系统。这种多因素评估可提高生存、有意义的功能恢复和长期生活质量的可能性。