Leitner Lukas, Postruznik Magdalena, Draschl Alexander, Koutp Amir, Leithner Andreas, Sadoghi Patrick
Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), LMU University Hospital, Munich, Germany.
Department of Orthopedics and Trauma, Medical University of Graz, Graz, Austria.
Arch Orthop Trauma Surg. 2025 Jul 21;145(1):381. doi: 10.1007/s00402-025-05979-6.
The mix and match (stem and cup from different manufacturers/systems, MM) approach in primary total hip arthroplasty (THA) involves combining components from different manufacturers. Despite various configurations discussed in literature and evidence supporting the safety of MM, controversy persists regarding safety and long term outcomes compared to matched components. Our study aimed to compare the revision rates of MM versus matched components.
Two databases were searched for English full-text articles published until January, 2024 that evaluated revision rates after primary MM THA. Additionally, MM revision rates data was extracted from the German Arthroplasty Registry (EPRD). The Newcastle-Ottawa Scale (NOS) for cohort studies was used for quality assessment.
Three national and one hospital registry studies were included, of which three demonstrate MM as a common practice (19-24%). All studies found comparable revision rates for MM cohorts, or even slightly improved survival rates in MM cohorts concerning revision rate and PROMs, mostly lacking clinical relevance. These findings align with the data reported in the EPRD, with revision rates of approximately 3.6% after 6 years in both MM and matched THA.
Employing MM in primary THA presents a feasible and safe approach, capable of providing custom fit tailored to individual patients with revision rates comparable to those of matched THA.
初次全髋关节置换术(THA)中的混合搭配(不同制造商/系统的柄和髋臼杯,MM)方法涉及组合来自不同制造商的组件。尽管文献中讨论了各种配置且有证据支持MM的安全性,但与匹配组件相比,其安全性和长期结果仍存在争议。我们的研究旨在比较MM与匹配组件的翻修率。
检索两个数据库,查找截至2024年1月发表的评估初次MM THA后翻修率的英文全文文章。此外,从德国关节置换登记处(EPRD)提取MM翻修率数据。队列研究的纽卡斯尔-渥太华量表(NOS)用于质量评估。
纳入三项国家和一项医院登记研究,其中三项表明MM是一种常见做法(19%-24%)。所有研究发现MM队列的翻修率相当,甚至在MM队列中,就翻修率和患者报告的结局测量指标(PROMs)而言,生存率略有提高,但大多缺乏临床相关性。这些发现与EPRD报告的数据一致,MM和匹配的THA在6年后的翻修率约为3.6%。
在初次THA中采用MM是一种可行且安全的方法,能够为个体患者提供定制贴合,其翻修率与匹配的THA相当。