Janardhanan Mahija, Suresh Rakesh, Savithri Vindhya, Krishnadas Arjun, Subash Pramod, Smitha N V, Aravind Thara, Mathew Lisha
Department of Oral & Maxillofacial Pathology & Microbiology, Amrita Vishwa Vidyapeetham, Amrita Institute of Medical Sciences Amrita School of Dentistry, AIMS Campus, Ponekkara (P.O), 682041, Kochi, Kerala, India.
Department of Craniomaxillofacial Surgery, Amrita Vishwa Vidyapeetham, Amrita Institute of Medical Sciences, Amrita School of Dentistry, AIMS Campus, Ponekkara (P.O), Kochi, Kerala, India.
Head Neck Pathol. 2025 Jul 21;19(1):90. doi: 10.1007/s12105-025-01828-5.
Mucoepidermoid carcinoma (MEC) is the most common malignant neoplasm of salivary gland origin, accounting for approximately 27% of all salivary gland malignancies. While it frequently involves the parotid gland, intraoral cases show a predilection for the palate. Rarely, MEC can arise within the facial skeleton, where it is the most common salivary gland tumor to occur intraosseously. Intraosseous MECs of the jaws are extremely rare and often present diagnostic challenges due to their clinical resemblance to more common jaw lesions. We present a rare case of intraosseous MEC in a 52-year-old male, initially presenting as a recurrent cystic lesion in the maxilla. The case underscores the diagnostic difficulty posed by its unusual histopathological features.
黏液表皮样癌(MEC)是唾液腺来源最常见的恶性肿瘤,约占所有唾液腺恶性肿瘤的27%。虽然它常累及腮腺,但口内病例多见于腭部。MEC极少发生于面骨内,是面骨内最常见的唾液腺肿瘤。颌骨内黏液表皮样癌极为罕见,因其临床表现与更常见的颌骨病变相似,常带来诊断挑战。我们报告一例52岁男性颌骨内黏液表皮样癌罕见病例,最初表现为上颌骨反复出现的囊性病变。该病例凸显了其不寻常的组织病理学特征所带来的诊断困难。