Oral and Maxillofacial Surgery Resident, Nassau University Medical Center, East Meadow, NY, USA.
Oral and Maxillofacial Pathology Resident, Northwell Health, Long Island Jewish Medical Center, New Hyde Park, New York.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Feb;131(2):217-220. doi: 10.1016/j.oooo.2020.10.011. Epub 2020 Oct 16.
Mucoepidermoid carcinoma is the most common salivary gland malignancy, accounting for 27% of all salivary gland cancers. Identified in 1921 and first analyzed in 1945, mucoepidermoid carcinoma has demonstrated a widely diverse histology with several morphologic variants having been described. One rare feature is the formation of intratumoral bone, which has been previously reported once in the English language literature. Though the etiology of these calcifications is still not known, it is believed that this finding is independent of overall disease prognosis. This case report illustrates this unusual feature in a 48-year-old Hispanic woman who initially presented with a floor of mouth swelling. Computed tomography examination subsequently revealed a soft tissue mass with intralesional radiopacities. Despite its relative rarity, it is important for practitioners to be aware of this unique presentation in that it may help to avoid misdiagnosis and delays in treatment.
黏液表皮样癌是最常见的唾液腺癌，占所有唾液腺癌的 27%。这种肿瘤于 1921 年被发现，并于 1945 年首次进行分析，具有广泛多样的组织学特征，已经描述了几种形态学变异型。一个罕见的特征是肿瘤内骨的形成，这种情况以前在英语文献中仅报告过一次。尽管这些钙化的病因尚不清楚，但人们认为这种发现与疾病的总体预后无关。本病例报告说明了一位 48 岁西班牙裔女性的这种不寻常特征，她最初表现为口底肿胀。随后的计算机断层扫描检查显示软组织肿块内有局灶性不透射线影。尽管这种情况相对罕见，但对于医生来说，了解这种独特的表现非常重要，因为这可能有助于避免误诊和治疗延误。
