Sheehan Mia, Dau Hallie, AboMoslim Maryam, Naguti Priscilla, Mwandacha Nelly, Booth Amy, Ruck Candice, Smith Laurie, Orem Jackson, Ogilvie Gina, Nakisige Carolyn
Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
Women's Health Research Institute, Vancouver, Canada.
PLOS Glob Public Health. 2025 Jul 21;5(7):e0003918. doi: 10.1371/journal.pgph.0003918. eCollection 2025.
Uganda has one of the highest incidence rates of cervical cancer in the world. Although this impacts all women, women living with human immunodeficiency virus (HIV) experience an increased risk for developing cervical cancer. This study aims to compare how HIV-positive and HIV-negative women in a remote sub-county in Uganda access health services to inform consideration of potential HIV and HPV-based cervical cancer screening integration at the community level. Women were recruited for this cross-sectional study door-to-door by village health teams if they had no prior screening or treatment of cervical cancer, no previous hysterectomy, were 30-49 years old residents of the South Busoga District Reserve, and could provide verbal informed consent. Participants completed a baseline survey, which included questions on HIV status, demographics, prior health history, past healthcare access and services recieved. The data was analyzed using bivariate descriptive statistics. Among the 1437 participants included in the analysis, 8.8% were HIV-positive. The majority of the respondents were between 30-34 years of age, were married, had received primary education or higher, and were farmers. The majority of women in both groups had accessed outreach visits (HIV-positive = 89.0%, HIV-negative = 85.8%) and health centres (HIV-positive = 96.1%, HIV-negative = 80.2%). The most commonly received services among both groups of women at outreach visits and health centres were immunization and antenatal care, respectively. Our study demonstrated that there were no significant differences in healthcare access between HIV-positive and HIV-negative women in rural Uganda. Additionally, the high usage of healthcare services by women living with HIV suggests that the integration of cervical cancer and HIV screening may facilitate early detection and prevention of cervical cancer among this population. This can reduce the burden of disease in Uganda and further contribute to the World Health Organization's initiative to eradicate cervical cancer.
乌干达是世界上宫颈癌发病率最高的国家之一。尽管这影响到所有女性,但感染人类免疫缺陷病毒(HIV)的女性患宫颈癌的风险更高。本研究旨在比较乌干达一个偏远次县的HIV阳性和HIV阴性女性获取医疗服务的方式,以为在社区层面考虑将基于HIV和人乳头瘤病毒(HPV)的宫颈癌筛查整合提供参考。如果女性此前未接受过宫颈癌筛查或治疗、未做过子宫切除术、年龄在30至49岁之间且是南布索加区保护区的居民,并能提供口头知情同意书,则由村卫生团队挨家挨户招募参加这项横断面研究。参与者完成了一项基线调查,其中包括有关HIV状况、人口统计学、既往健康史、过去获得的医疗服务及接受的治疗等问题。数据采用双变量描述性统计进行分析。在纳入分析的1437名参与者中,8.8%为HIV阳性。大多数受访者年龄在30至34岁之间,已婚,接受过小学或以上教育,且为农民。两组中的大多数女性都接受过外展服务(HIV阳性=89.0%,HIV阴性=85.8%)和前往过健康中心(HIV阳性=96.1%,HIV阴性=80.2%)。两组女性在外展服务和健康中心最常接受的服务分别是免疫接种和产前护理。我们的研究表明,乌干达农村地区的HIV阳性和HIV阴性女性在获得医疗服务方面没有显著差异。此外,感染HIV的女性对医疗服务的高使用率表明,将宫颈癌筛查与HIV筛查整合可能有助于在这一人群中早期发现和预防宫颈癌。这可以减轻乌干达的疾病负担,并进一步推动世界卫生组织根除宫颈癌的倡议。