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消极情绪对接受肩关节置换术的类风湿性关节炎患者疼痛的调节作用。

The moderating role of negative affect on pain in patients with rheumatoid arthritis who have undergone shoulder arthroplasty.

作者信息

Asimina Lazaridou, Tim Schneller, Daniela Brune, Robert Edwards, Markus Scheibel

机构信息

Department for Shoulder and Elbow Surgery, Schulthess Clinic, Zürich, Switzerland.

Department of Anesthesiology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.

出版信息

J Orthop Surg Res. 2025 Jul 21;20(1):686. doi: 10.1186/s13018-025-06109-z.

Abstract

OBJECTIVE

Patients with rheumatoid arthritis undergoing shoulder arthroplasty often experience significant pain and functional limitations. Improvements in physical outcomes are well-documented, but psychological factors like negative affect remains underexplored. This study aimed to examine whether changes in negative affect moderate the relationship between functional and pain in rheumatoid arthritis undergoing shoulder arthroplasty.

METHODS

We analyzed 92 patients with rheumatoid arthritis undergoing shoulder arthroplasty. Baseline and 6-month postoperative outcomes were assessed, including pain, shoulder function (SPADI), and negative affect. Moderation analysis was conducted to examine whether changes in negative affect influenced the relationship between functional improvements and pain reduction.

RESULTS

The majority of patients were female (80%) with a mean age of 65 ± 11.1 years. Postoperative assessments showed significant improvements in pain and function. Pain scores decreased from a mean of 5.6 (SD = 2.6) to 1.2 (SD = 1.7) (p <.001), while SPADI scores improved from 63.7 (SD = 18.7) to 24.7 (SD: 15.9), (p <.001). Negative affect showed a reduction from 1.4 (SD = 0.7) to 1.2 (SD: 0.4), (p =.067). Persistent pain was present in 16% of patients postoperatively. Moderation analysis revealed a significant interaction between improvements in function and changes in negative affect on pain (β = 0.16, p =.017), suggesting that patients with concurrent emotional improvement experienced enhanced pain relief.

CONCLUSION

Shoulder arthroplasty in patients with rheumatoid arthritis reduces pain and improves function. Notably, improvements in negative affect may amplify the benefit of functional recovery on pain outcomes. These findings highlight the importance of integrating psychological well-being into postoperative care for this population.

摘要

目的

接受肩关节置换术的类风湿性关节炎患者常经历显著疼痛和功能受限。身体状况改善已有充分记录,但诸如消极情绪等心理因素仍未得到充分研究。本研究旨在探讨消极情绪的变化是否会调节类风湿性关节炎患者接受肩关节置换术后功能与疼痛之间的关系。

方法

我们分析了92例接受肩关节置换术的类风湿性关节炎患者。评估了基线和术后6个月的结果,包括疼痛、肩部功能(SPADI)和消极情绪。进行了调节分析,以检验消极情绪的变化是否影响功能改善与疼痛减轻之间的关系。

结果

大多数患者为女性(80%),平均年龄65±11.1岁。术后评估显示疼痛和功能有显著改善。疼痛评分从平均5.6(标准差=2.6)降至1.2(标准差=1.7)(p<.001),而SPADI评分从63.7(标准差=18.7)提高到24.7(标准差:15.9),(p<.001)。消极情绪从1.4(标准差=0.7)降至1.2(标准差:0.4),(p=.067)。术后16%的患者仍存在持续性疼痛。调节分析显示功能改善与消极情绪变化对疼痛的影响之间存在显著交互作用(β=0.16,p=.017),表明情绪同时改善的患者疼痛缓解增强。

结论

类风湿性关节炎患者的肩关节置换术可减轻疼痛并改善功能。值得注意的是,消极情绪的改善可能会放大功能恢复对疼痛结果的益处。这些发现凸显了将心理健康纳入该人群术后护理的重要性。

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