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手术切除肾结石有助于预防尿路感染复发吗?一项系统评价。

Does surgical removal of kidney stones help prevent the recurrence of urinary tract infections? A systematic review.

作者信息

Man Michelle Yuki, Somani Bhaskar, Pietropaolo Amelia

机构信息

Faculty of Medicine, University of Southampton.

Department of Urology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

出版信息

Curr Opin Urol. 2025 Jul 22. doi: 10.1097/MOU.0000000000001328.

Abstract

PURPOSE OF REVIEW

Kidney stones disease (KSD) and urinary tract infections (UTIs) can be associated and reciprocally causal. Aim of this study is to understand the association between stone-free rate and infection clearance or recurrence after surgery.

RECENT FINDINGS

Studies are suggesting that removing stones may help to prevent UTIs. A systematic review was done to look at the relationship between UTIs and kidney stones and to find out whether stone removal surgery can help to reduce UTIs. The systematic review as done as per PRISMA checklist and three databases (Ovid MEDLINE, Cochrane Library and Embase) were searched for articles reporting on patients with recurrent UTIs and kidney stone surgery. All studies in English language were included with 1009 articles identified between 2000 and 2024.In the 10 studies finally selected, 1731 stones procedures were performed. Nine studies demonstrated a significant correlation between stone clearance and resolution of urinary tract infections.

SUMMARY

Surgical management of kidney stones appears to play a significant role in reducing UTI recurrence among patients with recurrent infections. Achieving stone clearance is associated with a higher likelihood of infection resolution and prolongation of infection-free intervals postoperatively.

摘要

综述目的

肾结石疾病(KSD)与尿路感染(UTIs)可能相关且互为因果。本研究的目的是了解手术后结石清除率与感染清除或复发之间的关联。

最新发现

研究表明,去除结石可能有助于预防尿路感染。进行了一项系统综述,以研究尿路感染与肾结石之间的关系,并确定结石清除手术是否有助于减少尿路感染。该系统综述按照PRISMA清单进行,检索了三个数据库(Ovid MEDLINE、Cochrane图书馆和Embase),以查找有关复发性尿路感染和肾结石手术患者的报道文章。纳入了所有英文研究,共识别出2000年至2024年间的1009篇文章。在最终选定的10项研究中,共进行了1731例结石手术。9项研究表明结石清除与尿路感染的缓解之间存在显著相关性。

总结

肾结石的手术治疗似乎在降低复发性感染患者的尿路感染复发率方面发挥着重要作用。实现结石清除与感染缓解的可能性增加以及术后无感染间隔期的延长相关。

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