Vivero-Alcívar Freddy Andrés, Escoto-Vásquez Lilibeth Stephania, Hernández-Ortega Oscar Rohel, Ramírez-Lugo Raymundo, Molotla-Fragoso Adriana
Department of Oral and Maxillofacial Surgery, Postgraduate and Research Division, Dental School, National Autonomous University of Mexico, Mexico City, Mexico.
Medical, Dental and Health Sciences Program, Postgraduate and Research Division, Dental School, National Autonomous University of Mexico, Mexico City, Mexico.
Case Rep Dent. 2025 Jul 14;2025:5602411. doi: 10.1155/crid/5602411. eCollection 2025.
Odontodysplasia is a dental anomaly that affects the maturation and formation of teeth, resulting in hypoplasia and hypocalcification of both enamel and dentin. It can affect one or several quadrants of the dentition, although generalized involvement is extremely rare. The exact cause is unclear, but trauma, infection, and nutritional or metabolic deficiencies have been suggested as possible contributing factors. Diagnosis requires a combination of clinical and radiological findings. Clinically, it presents as small teeth with yellow or brown discoloration, and it can affect both the primary and permanent dentition. Radiographically, there is reduced radiodensity, giving rise to a blurred or "ghost tooth" appearance. Histologically, these teeth show aprismatic enamel, interglobular dentin, and the presence of enamel-like calcifications known as enameloid conglomerates. Treatment depends on the extent of tooth involvement and the patient's age. This paper reports the case of a 31-year-old woman who presented with this rare anomaly in its generalized form, making her the oldest patient with this diagnosis reported in the literature.
牙发育异常是一种影响牙齿成熟和形成的牙齿异常，导致牙釉质和牙本质发育不全及钙化不全。它可影响牙列的一个或几个象限，尽管全身性受累极为罕见。确切病因尚不清楚，但创伤、感染以及营养或代谢缺陷被认为是可能的促成因素。诊断需要结合临床和影像学检查结果。临床上，表现为牙齿小且呈黄色或棕色变色，可影响乳牙列和恒牙列。在影像学上，放射密度降低，呈现出模糊或“鬼牙”外观。组织学上，这些牙齿表现为无棱柱形牙釉质、球间牙本质，以及存在称为类釉质团块的类牙釉质钙化。治疗取决于牙齿受累程度和患者年龄。本文报告了一名31岁女性的病例，她出现了这种罕见异常的全身性表现，使其成为文献报道中患有该诊断的最年长患者。
