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胰源性腹水:一项具有挑战性的诊断与复杂的管理

Hemosuccus Pancreaticus: A Challenging Diagnosis and Complex Management.

作者信息

Hassanien Ahmed, Motam Abdullah

机构信息

Internal Medicine, East Lancashire University Hospitals NHS Trust, Blackburn, GBR.

Gastroenterology, Royal Blackburn Teaching Hospital, Blackburn, GBR.

出版信息

Cureus. 2025 Jun 19;17(6):e86403. doi: 10.7759/cureus.86403. eCollection 2025 Jun.

DOI:10.7759/cureus.86403
PMID:40693063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12277924/
Abstract

Hemosuccus pancreaticus (HP) is an uncommon and infrequently reported cause of upper gastrointestinal bleeding. It is defined as a hemorrhage into the pancreatic duct, which subsequently drains into the duodenum via the ampulla of Vater. The condition is typically associated with underlying pancreatic pathology, such as pancreatitis, pseudocysts, or vascular abnormalities, including splenic artery aneurysms. Clinically, HP presents with intermittent gastrointestinal bleeding, epigastric pain, and a drop in hemoglobin levels; features that often delay diagnosis due to their non-specific and episodic nature. Early recognition is essential, as the condition carries a high risk of morbidity and mortality if not promptly managed. We present a diagnostically challenging case of HP in a frail patient with multiple comorbidities, highlighting the importance of clinical vigilance and multidisciplinary coordination.

摘要

胰源性腹水(HP)是上消化道出血的一种罕见且报道较少的病因。它被定义为胰管内出血,随后经 Vater 壶腹排入十二指肠。这种情况通常与潜在的胰腺病变有关,如胰腺炎、假性囊肿或血管异常,包括脾动脉瘤。临床上,HP 表现为间歇性胃肠道出血、上腹部疼痛和血红蛋白水平下降;由于这些症状具有非特异性和发作性,常常导致诊断延迟。早期识别至关重要,因为如果不及时处理,该疾病会带来较高的发病率和死亡率。我们报告了一例患有多种合并症的体弱患者的 HP 诊断难题病例,强调了临床警惕性和多学科协作的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/554df531b3cf/cureus-0017-00000086403-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/d155315e4b91/cureus-0017-00000086403-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/1eccaa6ffe2f/cureus-0017-00000086403-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/83d60d819324/cureus-0017-00000086403-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/916bdfff2138/cureus-0017-00000086403-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/933eaf77fe34/cureus-0017-00000086403-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/79bac54ceadc/cureus-0017-00000086403-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/88e8264a37a1/cureus-0017-00000086403-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/554df531b3cf/cureus-0017-00000086403-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/d155315e4b91/cureus-0017-00000086403-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/1eccaa6ffe2f/cureus-0017-00000086403-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/83d60d819324/cureus-0017-00000086403-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/916bdfff2138/cureus-0017-00000086403-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/933eaf77fe34/cureus-0017-00000086403-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/79bac54ceadc/cureus-0017-00000086403-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/88e8264a37a1/cureus-0017-00000086403-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f3/12277924/554df531b3cf/cureus-0017-00000086403-i08.jpg

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本文引用的文献

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The Tale of a Bleeding Tree: A Rare Case of Peripancreatic Variceal Hemorrhage Causing Hemosuccus Pancreaticus.一棵出血之树的故事:一例罕见的胰周静脉曲张出血导致胰源性血腹症
Cureus. 2022 Jul 21;14(7):e27106. doi: 10.7759/cureus.27106. eCollection 2022 Jul.
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Hemosuccus pancreaticus caused by gastroduodenal artery pseudoaneurysm associated with chronic pancreatitis: A case report and review of literature.
胃十二指肠动脉假性动脉瘤伴慢性胰腺炎所致胰源性门脉高压症:一例报告并文献复习
World J Clin Cases. 2021 Jan 6;9(1):236-244. doi: 10.12998/wjcc.v9.i1.236.
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Successful Management of Hemosuccus Pancreaticus due to Pancreatic Adenocarcinoma by Chemoradiotherapy.成功通过放化疗治疗因胰腺腺癌导致的胰性出血。
Intern Med. 2020 Sep 1;59(17):2135-2141. doi: 10.2169/internalmedicine.4372-19. Epub 2020 Jun 2.
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