Rammohan Ashwin, Palaniappan Ravichandran, Ramaswami Sukumar, Perumal Senthil Kumar, Lakshmanan Anand, Srinivasan U P, Ramasamy Ravi, Sathyanesan Jeswanth
Institute of Surgical Gastroenterology & Liver Transplantation, Centre for GI Bleed, Division of HPB Diseases, Stanley Medical College Hospital, Old Jail Road, Chennai 600 001, India.
ISRN Radiol. 2013 Feb 28;2013:191794. doi: 10.5402/2013/191794. eCollection 2013.
Background. Hemosuccus pancreaticus (HP) is a very rare and obscure cause of upper gastrointestinal bleeding. Due to its rarity, the diagnostic and therapeutic strategy for the management of this potentially life threatening problem remains undefined. The objective of our study is to highlight the challenges in the diagnosis and management of HP and to formulate a protocol to effectively and safely manage this condition. Methods. We retrospectively reviewed the records of all patients who presented with HP over the last 15 years at our institution between January 1997 and December 2011. Results. There were a total of 51 patients with a mean age of 32 years. Nineteen patients had chronic alcoholic pancreatitis; twenty-six, five, and one patient had tropical pancreatitis, acute pancreatitis, and idiopathic pancreatitis, respectively. Six patients were managed conservatively. Selective arterial embolization was attempted in 40 of 45 (89%) patients and was successful in 29 of the 40 (72.5%). 16 of 51 (31.4%) patients required surgery. Overall mortality was 7.8%. Length of followup ranged from 6 months to 15 years. Conclusions. Upper gastrointestinal bleeding in a patient with a history of chronic pancreatitis could be caused by HP. All hemodynamically stable patients with HP should undergo prompt initial angiographic evaluation, and if possible, embolization. Hemodynamically unstable patients and those following unsuccessful embolization should undergo emergency haemostatic surgery. Centralization of GI bleed services along with a multidisciplinary team approach and a well-defined management protocol is essential to reduce the mortality and morbidity of this condition.
背景。胰源性腹水(HP)是上消化道出血一种非常罕见且不明的病因。由于其罕见性,对于这种潜在危及生命问题的诊断和治疗策略仍不明确。我们研究的目的是突出HP诊断和管理中的挑战,并制定一个有效且安全管理这种情况的方案。方法。我们回顾性分析了1997年1月至2011年12月期间在我们机构过去15年中所有出现HP的患者的记录。结果。共有51例患者,平均年龄32岁。19例患者患有慢性酒精性胰腺炎;26例、5例和1例患者分别患有热带胰腺炎、急性胰腺炎和特发性胰腺炎。6例患者接受了保守治疗。45例患者中的40例(89%)尝试了选择性动脉栓塞,其中40例中的29例(72.5%)成功。51例患者中的16例(31.4%)需要手术。总体死亡率为7.8%。随访时间从6个月到15年不等。结论。有慢性胰腺炎病史的患者上消化道出血可能由HP引起。所有血流动力学稳定的HP患者应立即接受初步血管造影评估,如有可能,进行栓塞。血流动力学不稳定的患者以及栓塞失败的患者应接受紧急止血手术。集中胃肠道出血服务,采用多学科团队方法和明确的管理方案对于降低这种情况的死亡率和发病率至关重要。