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探索鼻出血的病因风险因素及其关联:一项针对印度一家三级护理中心500名患者的横断面研究。

Exploring Etiological Risk Factors and Their Association With Epistaxis: A Cross-Sectional Study on 500 Patients in a Tertiary Care Centre in India.

作者信息

Podder Amrit, Aggarwal Shivam, Shivgotra Dikshit, Khodnapur Jyoti P

机构信息

Department of Physiology, Teerthanker Mahaveer Medical College and Research Centre, Teerthanker Mahaveer University, Moradabad, IND.

Department of Ear, Nose, and Throat, Head and Neck Surgery, Venkateshwara Institute of Medical Sciences, Gajraula, IND.

出版信息

Cureus. 2025 Jun 21;17(6):e86488. doi: 10.7759/cureus.86488. eCollection 2025 Jun.

DOI:10.7759/cureus.86488
PMID:40693070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12278786/
Abstract

Introduction The clinical presentations of epistaxis share a wide spectrum, ranging from minor, self-limiting bleeds to life-threatening hemorrhages, which often require immediate intervention. Our cross-sectional study was conducted to bridge that gap in this direction, focusing on the determination of possible risk factors associated with epistaxis, which undertakes a comprehensive analysis of 500 cases of it in a tertiary care centre in India. Materials and methods A total of 500 patients with epistaxis were analyzed for their risk factor association using SPSS software version 27 (IBM Inc., Armonk, New York). Results We observed the highest association of epistaxis with hypertension (42.8%), and we also found that males share a higher frequency (62.4%) of hypertension as compared to females. Conclusion We conclude by establishing that hypertension, nasal trauma, and anatomical anomalies such as deviated nasal septum (DNS) are the primary independent predictors for epistaxis and recommend targeted preventive and therapeutic strategies to reduce morbidity and recurrence.

摘要

引言 鼻出血的临床表现多种多样,从轻微的、可自行停止的出血到危及生命的大出血,后者往往需要立即干预。我们开展了这项横断面研究,以期在这方面弥补差距,重点是确定与鼻出血相关的可能危险因素,该研究对印度一家三级医疗中心的500例鼻出血病例进行了全面分析。材料与方法 我们使用SPSS 27版软件(IBM公司,纽约州阿蒙克)对总共500例鼻出血患者的危险因素关联进行了分析。结果 我们观察到鼻出血与高血压的关联最为密切(42.8%),并且我们还发现,男性高血压的发生率(62.4%)高于女性。结论 我们通过研究确定,高血压、鼻外伤以及鼻中隔偏曲(DNS)等解剖异常是鼻出血的主要独立预测因素,并建议采取有针对性的预防和治疗策略以降低发病率和复发率。

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本文引用的文献

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The Role of Serum Erythropoietin (EPO) and Vascular Endothelial Growth Factor (VEGF) in Pulse Wave Velocity (PWV) Among Hypertensive Patients: A Cross-Sectional Study.血清促红细胞生成素(EPO)和血管内皮生长因子(VEGF)在高血压患者脉搏波速度(PWV)中的作用:一项横断面研究。
Cureus. 2024 Jun 15;16(6):e62416. doi: 10.7759/cureus.62416. eCollection 2024 Jun.
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Unravelling the Intricate Relationship Between Oxidative Stress and Endothelial Dysfunction in Hypertension.揭示高血压中氧化应激与内皮功能障碍之间的复杂关系
Cureus. 2024 May 28;16(5):e61245. doi: 10.7759/cureus.61245. eCollection 2024 May.
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Effectiveness of reflective learning in skill-based teaching among postgraduate anesthesia students: An outcome-based study using video annotation tool.反思性学习在麻醉学研究生基于技能教学中的有效性:一项使用视频注释工具的基于结果的研究。
Med J Armed Forces India. 2021 Feb;77(Suppl 1):S202-S207. doi: 10.1016/j.mjafi.2020.12.028. Epub 2021 Feb 2.
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Epistaxis: Revisited.鼻出血:再探讨。
Indian J Otolaryngol Head Neck Surg. 2020 Dec;72(4):480-483. doi: 10.1007/s12070-020-01930-w. Epub 2020 Jul 6.
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Association of Hypertension With the Risk and Severity of Epistaxis.高血压与鼻出血风险及严重程度的关联
JAMA Otolaryngol Head Neck Surg. 2020 Sep 10;147(1):1-7. doi: 10.1001/jamaoto.2020.2906.
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Clinical Practice Guideline: Nosebleed (Epistaxis).临床实践指南:鼻出血(鼻衄)。
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Association between Hypertension and Epistaxis: Systematic Review and Meta-analysis.高血压与鼻出血之间的关联:系统评价与荟萃分析
Otolaryngol Head Neck Surg. 2017 Dec;157(6):921-927. doi: 10.1177/0194599817721445. Epub 2017 Jul 25.
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Epistaxis: A retrospective clinical study.鼻出血:一项回顾性临床研究。
Indian J Otolaryngol Head Neck Surg. 2005 Apr;57(2):125-9. doi: 10.1007/BF02907666.
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