Habbas Ahmad, Althunibat Ismail, Elemian Shatha, Okwesili Byron, Abiola Abdul Aishat, Sorour Laith, Al Radaideh Amro, Fedida Andre
Internal Medicine, Saint Michael's Medical Center, Newark, USA.
Gastroenterology and Hepatology, Saint Michael's Medical Center, Newark, USA.
Cureus. 2025 Jun 21;17(6):e86486. doi: 10.7759/cureus.86486. eCollection 2025 Jun.
This case report presents a rare clinical manifestation of uterine spindle cell sarcoma, an aggressive and uncommon malignancy, in a 79-year-old female patient. The patient presented with lower gastrointestinal (GI) bleeding, constipation, and significant weight loss. Colonoscopy identified an infiltrative, ulcerated mass within the sigmoid colon, later confirmed by biopsy as a high-grade spindle cell sarcoma of uterine origin. Given the unresectable status of the mass, chemotherapy was initiated as the primary treatment. This report discusses the diagnostic challenges and highlights the importance of considering atypical presentations in patients with lower GI bleeding and weight loss.
本病例报告展示了一名79岁女性患者子宫梭形细胞肉瘤这一罕见的临床表现,该肿瘤是一种侵袭性且不常见的恶性肿瘤。患者出现下消化道出血、便秘及显著体重减轻。结肠镜检查发现乙状结肠内有一个浸润性溃疡肿物,活检后来证实为子宫来源的高级别梭形细胞肉瘤。鉴于肿物无法切除,开始以化疗作为主要治疗手段。本报告讨论了诊断方面的挑战,并强调了在有下消化道出血和体重减轻的患者中考虑非典型表现的重要性。