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鼻中隔成形术的临床实践与结果——瑞典2014年至2023年11714例手术的回顾性研究

Clinical Practice and Outcome of Septoplasty-A Retrospective Study of 11,714 Surgeries in Sweden 2014-2023.

作者信息

Sunnergren Ola, Alexandersson Cecilia, Broström Anders, Eliasson Fredrik, Jangard Mattias, Lilja Ylva, Pakpour Amir, Sandelin Kristoffer, Ahlström-Emanuelsson Cecilia

机构信息

Department of Otorhinolaryngology Sahlgrenska Academy, Gothenburg University Gothenburg Sweden.

Region Västra Götaland, Sahlgrenska University Hospital Department of Otorhinolaryngology Gothenburg Sweden.

出版信息

Laryngoscope Investig Otolaryngol. 2025 Jul 21;10(4):e70199. doi: 10.1002/lio2.70199. eCollection 2025 Aug.

DOI:10.1002/lio2.70199
PMID:40693163
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12278690/
Abstract

OBJECTIVES

Although septoplasty is frequently performed in patients with nasal obstruction, studies on clinical practice and real-life outcomes are sparse. This study aimed to describe the clinical practice, characteristics of septoplasty patients, patient-reported outcomes and complications, as well as predictors for a successful outcome in a comprehensive national longitudinal database.

METHODS

All patients, > 18 years of age, registered in the Swedish Quality Register for Septoplasty (SQRS) between 2014 and 2023 were included in the study ( = 11,714). A multivariate logistic regression analysis was used to search for predictors of a successful outcome (i.e., no or mild self-reported nasal obstruction).

RESULTS

Clinical practice was influenced by the surgical unit. A successful outcome was reported in 59.9% of the patients. Predictors for a successful outcome were higher age, more recent surgery, unilateral subjective nasal obstruction, no nighttime nasal obstruction, and no smoking. Almost one in four patients reported a chronic complication from surgery after 12 months.

CONCLUSION

There is an unwarranted diversity in Swedish septoplasty practice, which illustrates a lack of knowledge of best practices. The patient-reported outcome, where only six of 10 patients had no or mild nasal obstruction at follow-up, indicates room for improvement.

LEVEL OF EVIDENCE

摘要

目的

尽管鼻中隔成形术常用于治疗鼻塞患者,但关于临床实践和实际治疗效果的研究却很少。本研究旨在通过一个全面的全国纵向数据库,描述鼻中隔成形术的临床实践、患者特征、患者报告的治疗效果和并发症,以及手术成功的预测因素。

方法

纳入2014年至2023年间在瑞典鼻中隔成形术质量登记处(SQRS)登记的所有18岁以上患者(n = 11714)。采用多因素逻辑回归分析寻找手术成功(即自我报告无或轻度鼻塞)的预测因素。

结果

临床实践受手术科室的影响。59.9%的患者报告手术成功。手术成功的预测因素包括年龄较大、近期手术、单侧主观鼻塞、无夜间鼻塞和不吸烟。近四分之一的患者在术后12个月报告有手术相关的慢性并发症。

结论

瑞典鼻中隔成形术的实践存在不必要的差异,这表明缺乏对最佳实践的了解。患者报告的治疗效果显示,随访时每10名患者中只有6名无或仅有轻度鼻塞,这表明仍有改进空间。

证据等级

4级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843a/12278690/ed4409f8e443/LIO2-10-e70199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843a/12278690/3f4000eb7dc4/LIO2-10-e70199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843a/12278690/ed4409f8e443/LIO2-10-e70199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843a/12278690/3f4000eb7dc4/LIO2-10-e70199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843a/12278690/ed4409f8e443/LIO2-10-e70199-g001.jpg

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本文引用的文献

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On the outcome of septoplasty.鼻中隔成形术的结果。
Rhinology. 2024 Aug 1;62(4):509-510. doi: 10.4193/Rhin23.472.
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Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial.鼻中隔成形术与药物治疗对鼻气道阻塞的临床疗效比较:多中心、开放标签、随机对照试验。
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Laryngoscope Investig Otolaryngol. 2023 Mar 6;8(2):357-366. doi: 10.1002/lio2.1036. eCollection 2023 Apr.
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Usage of Surgical Antibiotic Prophylaxis in Routine Otolaryngologic Surgeries in Turkey.土耳其常规耳鼻喉科手术中外科抗生素预防的使用情况。
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Evaluation of the clinical efficacy of nasal surgery in the treatment of obstructive sleep apnoea.评价鼻手术治疗阻塞性睡眠呼吸暂停的临床疗效。
Am J Otolaryngol. 2022 Jan-Feb;43(1):103158. doi: 10.1016/j.amjoto.2021.103158. Epub 2021 Jul 30.
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Is postoperative nasal packing after septoplasty safe? A systematic review and meta-analysis of randomized controlled studies.鼻中隔成形术后是否需要鼻腔填塞?随机对照研究的系统评价和荟萃分析。
Rhinology. 2021 Aug 1;59(4):340-351. doi: 10.4193/Rhin21.057.
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