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用于检测食品中霉菌毒素和海洋生物毒素的光电化学生物传感器的最新进展:识别与信号放大策略

Recent Advances in Photoelectrochemical Biosensors for Detection of Mycotoxins and Marine Biotoxins in Food: Identification and Signal Amplification Strategy.

作者信息

Zhou Yunlei, Yin Huanshun

机构信息

College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, PR, China.

Key Laboratory of Marine Resource Chemistry and Food Technology (TUST), Ministry of Education, College of Marine and Environmental Sciences, Tianjin University of Science and Technology, Tianjin 300457, PR China.

出版信息

J Agric Food Chem. 2025 Jul 30;73(30):18561-18584. doi: 10.1021/acs.jafc.5c05793. Epub 2025 Jul 22.

Abstract

Mycotoxins and marine biotoxins are highly toxic metabolites produced by fungi and phytoplankton, respectively. They can enter the body of humans and animals through feed or food, causing acute or chronic toxicity on the endocrine and nervous systems, which eventually pose a serious threat to humans and animals' life. Development of inexpensive, fast, specific, and sensitive analytical methods for mycotoxin and marine biotoxin detection in foodstuffs and the environment is of great importance. Owing to the advantages of simple operation, inexpensive and small-sized instrument, high detection sensitivity and selectivity, ease in achieving intelligence, and real-time detection, photoelectrochemical sensors have been applied to detect these toxins. This review summarized the application of photoelectrochemical sensors for mycotoxin and marine biotoxin detection in recent years, especially the recognition approaches for mycotoxins and marine biotoxins and the signal amplification strategies for photoelectrochemical sensors. Ultimately, the current challenges and prospects in this field were also discussed.

摘要

霉菌毒素和海洋生物毒素分别是由真菌和浮游植物产生的高毒性代谢产物。它们可通过饲料或食物进入人类和动物体内,对内分泌和神经系统造成急性或慢性毒性,最终对人类和动物的生命构成严重威胁。开发用于食品和环境中霉菌毒素和海洋生物毒素检测的廉价、快速、特异且灵敏的分析方法具有重要意义。由于具有操作简单、仪器廉价且体积小、检测灵敏度和选择性高、易于实现智能化以及实时检测等优点,光电化学传感器已被应用于检测这些毒素。本文综述了近年来光电化学传感器在霉菌毒素和海洋生物毒素检测中的应用,特别是霉菌毒素和海洋生物毒素的识别方法以及光电化学传感器的信号放大策略。最后,还讨论了该领域当前面临的挑战和前景。

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