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小儿急性乳突炎:哪些因素影响CT扫描的开具及手术干预?一项多变量分析。

Pediatric Acute Mastoiditis: Which Factors Influence CT Scan Prescription and Surgical Intervention? A Multivariate Analysis.

作者信息

Lucidi Daniela, Reale Marella, Cantaffa Carla, Roncadi Leonardo, Frabboni Ilaria, Iughetti Lorenzo, Fernandez Ignacio Javier, Alicandri-Ciufelli Matteo, Marchioni Daniele

机构信息

Department of Otolaryngology - Head and Neck Surgery, University Hospital of Modena, Modena, Italy.

Department of Pediatrics, University Hospital of Modena, Modena, Italy.

出版信息

J Int Adv Otol. 2025 Jul 21;21(4):1-6. doi: 10.5152/iao.2025.251899.

DOI:10.5152/iao.2025.251899
PMID:40693582
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12317838/
Abstract

BACKGROUND

The aim of this study is to investigate factors associated with computed tomography (CT) scan prescription and surgical intervention in pediatric patients with acute mastoiditis (AM). METHODS: Children with AM admitted to Modena University Hospital over a 10-year period were retrospectively divided into 3 groups: those who did not undergo a CT scan nor surgery (Group A); those who underwent a CT scan but not surgery (Group B); and those who underwent CT scan and surgery (Group C). A multivariate analysis was performed to determine possible differences among groups in terms of clinical and laboratory variables. RESULTS: In total, 80 patients were included (57 Group A, 22 Group B, 13 Group C). Factors independently associated with CT scan prescription and surgical intervention were WBC count (P = .015 and .041, respectively), CRP (P = .001 and .003, respectively), and at-home antibiotic adminis-tration (P= .008 and .039, respectively). CONCLUSION: Laboratory parameters may be helpful in guiding pediatric AM management. Antibiotic treatment prior to admission is associated with a worse clinical picture.

摘要

背景

本研究旨在调查与急性乳突炎(AM)患儿计算机断层扫描(CT)检查医嘱及手术干预相关的因素。方法:回顾性分析在10年期间入住摩德纳大学医院的AM患儿,将其分为3组:未接受CT检查及手术的患儿(A组);接受CT检查但未接受手术的患儿(B组);接受CT检查及手术的患儿(C组)。进行多因素分析以确定各组在临床和实验室变量方面的可能差异。结果:共纳入80例患者(A组57例,B组22例,C组13例)。与CT检查医嘱及手术干预独立相关的因素分别为白细胞计数(P值分别为0.015和0.041)、C反应蛋白(CRP)(P值分别为0.001和0.003)以及在家中使用抗生素(P值分别为0.008和0.039)。结论:实验室参数可能有助于指导儿童AM的管理。入院前使用抗生素治疗与更差的临床情况相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f87/12317838/cba7e4aaf20e/jiao-21-4-251899_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f87/12317838/cba7e4aaf20e/jiao-21-4-251899_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f87/12317838/cba7e4aaf20e/jiao-21-4-251899_f001.jpg

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本文引用的文献

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Surgical interventions in acute complicated mastoiditis - is a cortical mastoidectomy always required? A 5-year retrospective cohort study.
Surgeon. 2025 Aug;23(4):229-232. doi: 10.1016/j.surge.2025.01.007. Epub 2025 Feb 15.
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Clinical characteristics and predictive factors of thrombotic complications in children with acute mastoiditis: a single center retrospective study.急性乳突炎患儿血栓形成并发症的临床特征及预测因素:一项单中心回顾性研究
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Int J Pediatr Otorhinolaryngol. 2025 Jan;188:112204. doi: 10.1016/j.ijporl.2024.112204. Epub 2024 Dec 16.
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Our experience on the management of acute mastoiditis in pediatric acute otitis media patients.我们在小儿急性中耳炎患者中急性乳突炎管理方面的经验。
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Otogenic Lateral Sinovenous Thrombosis in Children: A Case Series from a Single Centre and Narrative Review.儿童耳源性侧窦血栓形成:单中心病例系列及叙述性综述。
J Stroke Cerebrovasc Dis. 2020 Oct;29(10):105184. doi: 10.1016/j.jstrokecerebrovasdis.2020.105184. Epub 2020 Jul 31.
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Acute mastoiditis in children: contemporary opportunities and challenges.儿童急性乳突炎:当代机遇与挑战
J Laryngol Otol. 2020 May;134(5):434-439. doi: 10.1017/S0022215120000833. Epub 2020 May 28.
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Acta Biomed. 2020 Feb 17;91(1-S):54-59. doi: 10.23750/abm.v91i1-S.9259.
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Eur Arch Otorhinolaryngol. 2019 Nov;276(11):3051-3056. doi: 10.1007/s00405-019-05606-2. Epub 2019 Aug 27.
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