Alvisi V, Onofri W, Biasini L, Cappellari R, Massari M, Pavani F, Ruina M, D'Ambrosi A
Minerva Med. 1985 Nov 10;76(43):2037-42.
The results of a study conducted both on subjects affected by constitutional hyperbilirubinaemia (Gilbert's syndrome) and healthy subjects using the charge test with crystalline bilirubin are presented. The parameters which are involved in bilirubin kinetics were established by means of non linear regression methods (the Marquardt method). 19 Gilbert syndrome patients and 12 normal control subjects were studied. Important parameters readily applicable to clinical and diagnostic evaluation of subjects suffering from familial cholemia were identified.
本文展示了一项针对患有体质性高胆红素血症（吉尔伯特综合征）的受试者和健康受试者，使用结晶胆红素负荷试验的研究结果。通过非线性回归方法（马夸特法）确定了胆红素动力学所涉及的参数。研究了19例吉尔伯特综合征患者和12例正常对照受试者。确定了一些易于应用于家族性胆血症患者临床和诊断评估的重要参数。
