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一场全新的局面:一项回顾性队列研究,利用医疗管理数据揭示加拿大不列颠哥伦比亚省1型糖尿病患儿及时过渡到成人护理的预测因素。

A whole new ball game: a retrospective cohort study using healthcare administrative data to uncover predictors of timely transition from paediatric to adult type 1 diabetes care in British Columbia, Canada.

作者信息

Leung Joseph M W S, Chen Leo, Zhang Qian, Bone Jeffrey N, Amed S

机构信息

Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada

Vancouver General Hospital, Vancouver, British Columbia, Canada.

出版信息

BMJ Open. 2025 Jul 21;15(7):e099379. doi: 10.1136/bmjopen-2025-099379.

Abstract

OBJECTIVES

To assess predictors of timely transition to adult diabetes care among individuals diagnosed with type 1 diabetes during childhood and adolescence. We hypothesised that older age at the last paediatric visit and urban residency would be predictors of timely transition.

DESIGN

Retrospective cohort study using healthcare administrative data in a jurisdiction with a universal healthcare system.

PARTICIPANTS

2045 adolescents and young adults diagnosed with type 1 diabetes between the ages of 0.5 and 18 years.

PRIMARY AND SECONDARY OUTCOME MEASURES

We ascertained age at the last paediatric diabetes visit (LPDV), age at the first adult diabetes visit (FADV) and transition duration, defined as the time between LPDV and FADV. Timely transition was defined as a transition duration of <1 year. Logistic regression models were fitted to assess predictors of timely transition.

RESULTS

Only 31.3% of individuals saw an adult provider within 1 year of their LPDV. Each 1-year increase in the age at LPDV was associated with increased odds of timely transition (adjusted OR 1.82, 95% CI 1.71 to 1.93, p<0.001). Urban residency was also associated with increased odds of timely transition (adjusted OR 1.93, 95% CI 1.40 to 2.71, p<0.001). Sex and older age at diagnosis were not associated with timely transition in the multivariable regression models (p>0.05).

CONCLUSIONS

Older age at the LPDV and urban residency are associated with increased odds of timely transition. Interventions should be developed to help keep adolescents engaged in paediatric care until an older age before referring them to adult diabetes care. Limitations of this study include unmeasured confounding and limited generalisability to non-universal healthcare systems.

摘要

目的

评估儿童期和青少年期被诊断为1型糖尿病的个体及时转诊至成人糖尿病护理的预测因素。我们假设最后一次儿科就诊时年龄较大以及居住在城市是及时转诊的预测因素。

设计

在一个拥有全民医疗体系的辖区,利用医疗管理数据进行回顾性队列研究。

参与者

2045名年龄在0.5岁至18岁之间被诊断为1型糖尿病的青少年和青年成人。

主要和次要结局指标

我们确定了最后一次儿科糖尿病就诊时的年龄(LPDV)、首次成人糖尿病就诊时的年龄(FADV)以及转诊持续时间,定义为LPDV和FADV之间的时间。及时转诊定义为转诊持续时间<1年。采用逻辑回归模型评估及时转诊的预测因素。

结果

只有31.3%的个体在LPDV后1年内就诊于成人医疗服务提供者。LPDV时年龄每增加1岁,及时转诊的几率增加(调整后的比值比为1.82,95%置信区间为1.71至1.93,p<0.001)。居住在城市也与及时转诊的几率增加相关(调整后的比值比为1.93,95%置信区间为1.40至2.71,p<0.001)。在多变量回归模型中,性别和诊断时年龄较大与及时转诊无关(p>0.05)。

结论

LPDV时年龄较大和居住在城市与及时转诊的几率增加相关。应制定干预措施,帮助青少年在转诊至成人糖尿病护理之前,在较大年龄阶段仍参与儿科护理。本研究的局限性包括未测量的混杂因素以及对非全民医疗体系的普遍适用性有限。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f926/12281320/6c809351e6ee/bmjopen-15-7-g001.jpg

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