先天性青光眼的病因。遗传因素和非遗传因素。

Etiology of congenital glaucoma. Genetic and extragenetic factors.

作者信息

Bardelli A M, Hadjistilianou T, Frezzotti R

出版信息

Ophthalmic Paediatr Genet. 1985 Aug;6(1-2):265-70.

Abstract

Congenital glaucoma (simple, associated and secondary) has been studied for the frequency of mesodermal anomalies and malformations (skeletal changes, congenital heart diseases, neurological alterations). But congenital glaucoma is not due solely to genetic factors: it is more likely that most cases result from interaction between genetic predisposition and a combination of environmental causes.

摘要

先天性青光眼（单纯性、关联性和继发性）已针对中胚层异常和畸形（骨骼变化、先天性心脏病、神经改变）的发生率进行了研究。但先天性青光眼并非仅由遗传因素导致：大多数病例更有可能是遗传易感性与多种环境因素共同作用的结果。