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Treatment patterns of extracorporeal photopheresis in steroid-refractory graft versus host disease: A delphi study.

作者信息

Penack Olaf, Bacigalupo Andrea, Gavriilaki Eleni, Greinix Hildegard, Malard Florent, Michonneau David, Olivieri Attilio, Peric Zinaida, Sala Elisa, Solano Carlos, Wolff Daniel, Zeiser Robert

机构信息

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Tumorimmunology, Augustenburger Platz 1, 13353, Berlin, Germany.

Fondazione Policlinico Universitario A. Gemelli, Roma, Italy.

出版信息

Bone Marrow Transplant. 2025 Jul 22. doi: 10.1038/s41409-025-02687-y.

DOI:10.1038/s41409-025-02687-y
PMID:40696076
Abstract
摘要

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Treatment patterns of extracorporeal photopheresis in steroid-refractory graft versus host disease: A delphi study.体外光分离置换疗法治疗类固醇难治性移植物抗宿主病的模式：一项德尔菲研究。
Bone Marrow Transplant. 2025 Jul 22. doi: 10.1038/s41409-025-02687-y.
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Lower incidence of chronic graft--host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft--host disease following allogeneic stem cell transplantation.在异基因干细胞移植后对类固醇难治性急性移植物抗宿主病的治疗中，与单独使用鲁索替尼相比，鲁索替尼联合体外光分离置换术治疗后慢性移植物抗宿主病的发生率更低。
Haematologica. 2025 Jul 1;110(7):1536-1544. doi: 10.3324/haematol.2024.286824. Epub 2025 Mar 20.
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Extracorporeal photopheresis versus standard treatment for acute graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients.儿童造血干细胞移植后急性移植物抗宿主病的体外光化学疗法与标准治疗对比
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Extracorporeal photopheresis versus alternative treatment for chronic graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients.儿童造血干细胞移植后慢性移植物抗宿主病的体外光化学疗法与替代治疗对比
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Extracorporeal photopheresis versus standard treatment for acute graft-versus-host disease after haematopoietic stem cell transplantation in children and adolescents.体外光分离术与标准治疗在儿童和青少年造血干细胞移植后急性移植物抗宿主病中的比较。
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Extracorporeal photopheresis versus alternative treatment for chronic graft-versus-host disease after haematopoietic stem cell transplantation in children and adolescents.体外光分离术与其他治疗方案在儿童和青少年造血干细胞移植后慢性移植物抗宿主病中的比较。
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The concurrent administration of imatinib with extracorporeal photopheresis leads to complete and durable responses in patients with refractory sclerotic type chronic graft-versus-host disease.伊马替尼与体外光分离术同时给药可导致难治性硬化型慢性移植物抗宿主病患者完全和持久的反应。
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本文引用的文献

1
Prophylaxis and management of graft-versus-host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation.造血系统恶性肿瘤患者干细胞移植后移植物抗宿主病的预防和治疗：欧洲血液和骨髓移植学会更新的共识建议。
Lancet Haematol. 2024 Feb;11(2):e147-e159. doi: 10.1016/S2352-3026(23)00342-3. Epub 2024 Jan 3.
2
Extracorporeal photopheresis in acute and chronic steroid‑refractory graft-versus-host disease: an evolving treatment landscape.体外光分离术治疗急性和慢性激素难治性移植物抗宿主病：不断发展的治疗领域。
Leukemia. 2022 Nov;36(11):2558-2566. doi: 10.1038/s41375-022-01701-2. Epub 2022 Sep 24.
3
Efficacy and safety of ruxolitinib in steroid-refractory graft-versus-host disease: A meta-analysis.
芦可替尼治疗类固醇难治性移植物抗宿主病的疗效和安全性：一项荟萃分析。
Front Immunol. 2022 Aug 4;13:954268. doi: 10.3389/fimmu.2022.954268. eCollection 2022.
4
Nonrelapse mortality among patients diagnosed with chronic GVHD: an updated analysis from the Chronic GVHD Consortium.慢性移植物抗宿主病患者的非复发死亡率：慢性移植物抗宿主病联盟的更新分析。
Blood Adv. 2021 Oct 26;5(20):4278-4284. doi: 10.1182/bloodadvances.2021004941.
5
Ruxolitinib resistance or intolerance in steroid-refractory acute graft-versus-host disease - a real-world outcomes analysis.鲁索替尼在类固醇难治性急性移植物抗宿主病中的耐药性或不耐受性——一项真实世界结局分析
Br J Haematol. 2021 Nov;195(3):429-432. doi: 10.1111/bjh.17700. Epub 2021 Jul 12.
6
Evaluation of Ruxolitinib for Steroid-Refractory Chronic Graft-vs-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation.芦可替尼用于异基因造血干细胞移植后类固醇难治性慢性移植物抗宿主病的评估。
JAMA Netw Open. 2021 Jan 4;4(1):e2034750. doi: 10.1001/jamanetworkopen.2020.34750.
7
Refractory acute graft-versus-host disease: a new working definition beyond corticosteroid refractoriness.难治性急性移植物抗宿主病：超越激素抵抗的新工作定义。
Blood. 2020 Oct 22;136(17):1903-1906. doi: 10.1182/blood.2020007336.
8
Extracorporeal Photopheresis in Graft-versus-Host Disease.体外光化学疗法治疗移植物抗宿主病
Transfus Med Hemother. 2020 Jun;47(3):214-225. doi: 10.1159/000508169. Epub 2020 May 19.
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Transfusion. 2018 Aug;58(8):1973-1979. doi: 10.1111/trf.14649. Epub 2018 Apr 29.
10
Vascular access considerations for extracorporeal photopheresis.体外光化学疗法的血管通路考量
Transfusion. 2018 Feb;58 Suppl 1:590-597. doi: 10.1111/trf.14500.