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身体活动介导了体重状况与影响日常活动的疼痛之间的关系。

Physical activity mediates the relationship between weight status and pain impacting daily activities.

作者信息

Peterson Jessica A, Venturini Ashley, Larson Daniel J, Lu Yu, Larson Rebecca D, Black Christopher D

机构信息

Department of Health and Exercise Science, University of Oklahoma, Norman, OK, USA.

Department of Kinesiology, New Mexico State University, Las Cruces, NM, USA.

出版信息

Int J Obes (Lond). 2025 Jul 22. doi: 10.1038/s41366-025-01838-x.

Abstract

BACKGROUND

Individuals who have chronic pain experience reductions in physical activity (PA), quality of life, and physical capabilities, creating a debilitating cycle where decreased PA and increased weight exacerbate pain. This study aimed to examine associations between weight status, PA, and time spent in pain using a nationally representative sample, accounting for demographic factors.

METHODS

Using data from the 2011-2012 NHANES cycle, a comparison of pain groups with weight status and PA (total and type) and a mediation analysis using PA (total and type) as a mediator between weight status and time spent in pain were conducted.

RESULTS

Total PA groups differed in pain levels with those engaging in vigorous activity having the lowest prevalence in the "pain always" category (5.4%), and those with obesity had a higher prevalence of "pain always" (49.6%) compared to those with normal weight (19.5%) and those with overweight (30.9%). Total PA mediated the relationship between people with obesity and the amount of time spent in pain (effect:1.141; CI:0.456-1.837), that is, compared to those who have normal weight, those who have obesity were less likely to meet the total PA guideline, and subsequently likely to spend more days in pain. Breaking down PA by types, travel PA (effect:0.071; CI:0.024-0.152), moderate recreational PA (effect:0.041; CI:0.018-0.079), and vigorous recreational PA (effect:0.135; CI:0.035-0.279) significantly mediated the relationships between people with obesity and days spent in pain.

CONCLUSION

Findings suggest that vigorous PA is linked to lower pain prevalence. Additionally, PA significantly mediates the relationship between people with obesity and days spent in pain. While people with overweight alone was not associated with the number of days spent in pain, engaging in vigorous recreational activities was linked to reductions in days spent in pain for individuals with overweight, highlighting the importance of staying active to manage pain.

摘要

背景

患有慢性疼痛的个体身体活动(PA)、生活质量和身体能力下降,形成了一个恶性循环,即PA减少和体重增加会加剧疼痛。本研究旨在使用具有全国代表性的样本,考虑人口统计学因素,研究体重状况、PA与疼痛时长之间的关联。

方法

利用2011 - 2012年美国国家健康与营养检查调查(NHANES)周期的数据,对疼痛组与体重状况和PA(总量及类型)进行比较,并以PA(总量及类型)作为体重状况与疼痛时长之间的中介变量进行中介分析。

结果

PA总量组的疼痛水平存在差异,进行剧烈活动的人群在“总是疼痛”类别中的患病率最低(5.4%),肥胖者“总是疼痛”的患病率(49.6%)高于正常体重者(19.5%)和超重者(30.9%)。PA总量介导了肥胖者与疼痛时长之间的关系(效应:1.141;置信区间:0.456 - 1.837),也就是说,与正常体重者相比,肥胖者达到PA总量指南的可能性较小,因此可能会有更多天数处于疼痛中。按类型分解PA,出行PA(效应:0.071;置信区间:0.024 - 0.152)、中度休闲PA(效应:0.041;置信区间:0.018 - 0.079)和剧烈休闲PA(效应:0.135;置信区间:0.035 - 0.279)显著介导了肥胖者与疼痛天数之间的关系。

结论

研究结果表明,剧烈PA与较低的疼痛患病率相关。此外,PA显著介导了肥胖者与疼痛天数之间的关系。虽然仅超重者与疼痛天数无关,但进行剧烈休闲活动与超重个体的疼痛天数减少有关,这突出了保持活跃以控制疼痛的重要性。

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