Tian Gang, Wang Jinming, Zhu Jialiang, Hu Hengyu, Hao Yibin
Henan Province Hypertension Precision Prevention and Control Engineering Research Center, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, 450003, China.
Medical Genetics Institute of Henan Province, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, China.
BMC Public Health. 2025 Jul 22;25(1):2524. doi: 10.1186/s12889-025-23771-4.
This study aimed to examine whether loneliness mediate associations of family support with depression and the extent of interaction of family support and loneliness with depression in children and adolescents.
There were 2755 children and adolescents aged 18 and below from the China Family Panel Studies (CFPS) that participated in our study. Depression in children and adolescents was assessed by the Center for Epidemiologic Studies Depression Scale (CES-D). Data were analyzed using logistic regression models, mediation analysis models and the interaction effect models.
Of the 2,755 children and adolescents, 848 (30.8%) reported feelings of loneliness and 2,452 (88.7%) reported feelings of depression. The results of the multivariate logistic regression analysis indicated that, in comparison to children and adolescents who reported having family support, those who lacked such support exhibited a higher probability of experiencing loneliness (odds ratio (OR) = 1.668, 95% confidence interval (CI): (1.318-2.111) and depression (OR, 95%CI = 2.267, 1.402-3.664). The results of the mediation analysis indicated that loneliness exerted a partial mediating effect on the relationship between family support and depression (β=-0.087, P < 0.001), with a mediation proportion of 33.21%. No significant multiplicative or additive interactions were observed between family support and loneliness on depression.
The findings indicate that family support exerts a direct and indirect influence on depression, mediated by loneliness. The results suggest that parents should provide more support to children and adolescents to mitigate the risk of loneliness and underlying depression.
本研究旨在探讨孤独感是否介导家庭支持与抑郁之间的关联，以及家庭支持与孤独感在儿童和青少年中与抑郁的相互作用程度。
来自中国家庭追踪调查（CFPS）的2755名18岁及以下的儿童和青少年参与了我们的研究。儿童和青少年的抑郁情况通过流行病学研究中心抑郁量表（CES-D）进行评估。数据使用逻辑回归模型、中介分析模型和交互效应模型进行分析。
在2755名儿童和青少年中，848名（30.8%）报告有孤独感，2452名（88.7%）报告有抑郁感。多变量逻辑回归分析结果表明，与报告有家庭支持的儿童和青少年相比，缺乏家庭支持的儿童和青少年出现孤独感（优势比（OR）=1.668，95%置信区间（CI）：（1.318 - 2.111））和抑郁感（OR，95%CI = 2.267，1.402 - 3.664）的概率更高。中介分析结果表明，孤独感在家庭支持与抑郁之间的关系中发挥了部分中介作用（β=-0.087，P < 0.001），中介比例为33.21%。在抑郁方面，未观察到家庭支持与孤独感之间存在显著的相乘或相加交互作用。
研究结果表明，家庭支持对抑郁有直接和间接影响，孤独感起中介作用。结果表明，父母应给予儿童和青少年更多支持，以降低孤独感和潜在抑郁的风险。
