Gürsu Müjde, Sevimay Mehmet Altay, Çekmez Ertuğrul, Atak Seçen İpek, Şimşek Mehmet Bariş
Department of Oral and Maxillofacial Surgery, Gazi University Faculty of Dentistry, Ankara, Turkey.
Department of Oral Pathology, Gazi University Faculty of Dentistry, Ankara, Turkey.
Medicine (Baltimore). 2025 Jul 18;104(29):e43332. doi: 10.1097/MD.0000000000043332.
Dentinogenic ghost cell tumors (DGCTs) are rare odontogenic neoplasms constituting the solid variant of calcifying odontogenic cysts. Predominantly observed in adults, DGCTs are exceptionally rare in pediatric patients. This case report aims to contribute to the limited literature by presenting the clinical, radiographic, and histopathological findings of a pediatric patient with a DGCT and emphasizing the importance of early diagnosis.
A 14-year-old male presented with facial asymmetry in the left mandible.
Diagnostic imaging revealed a multilocular radiolucent lesion with impacted teeth, cortical expansion, and root resorption. Histopathological evaluation confirmed the DGCT diagnosis.
The lesion was treated conservatively with enucleation and curettage, followed by a 3-year follow-up.
Regular follow-ups demonstrated progressive bone regeneration with no evidence of recurrence. No postoperative complications were observed.
Because of their high recurrence rate and potential for transformation into dentinogenic ghost cell carcinoma, early diagnosis and long-term follow-up are crucial for effective management in DGCT cases.
牙源性影细胞肿瘤（DGCTs）是一种罕见的牙源性肿瘤，属于钙化牙源性囊肿的实性变体。DGCTs主要见于成年人，在儿科患者中极为罕见。本病例报告旨在通过展示一名患有DGCT的儿科患者的临床、影像学和组织病理学表现，并强调早期诊断的重要性，为有限的文献提供补充。
一名14岁男性因左下颌面部不对称前来就诊。
诊断性影像学检查显示一个多房性透射性病变，伴有阻生牙、皮质扩张和牙根吸收。组织病理学评估证实了DGCT的诊断。
对病变进行了保守治疗，采用摘除术和刮除术，随后进行了3年的随访。
定期随访显示骨组织逐渐再生，无复发迹象。未观察到术后并发症。
由于DGCTs复发率高且有转化为牙源性影细胞癌的可能，早期诊断和长期随访对于DGCT病例的有效管理至关重要。
