Salgado Inês, Vilares Miguel, Nogueira Ricardo, Rito Miguel, Rosa Filipa, Gomes Pedro
Department of Head and Neck Surgery, Instituto Português de Oncologia de Lisboa Francisco Gentil, Portugal.
Department of Head and Neck Surgery, Instituto Português de Oncologia de Lisboa Francisco Gentil, Portugal.
Int J Surg Case Rep. 2021 Apr;81:105651. doi: 10.1016/j.ijscr.2021.105651. Epub 2021 Feb 15.
Dentinogenic ghost cell tumor (DGCT) is an entity with about 60 cases reported in the literature. It is a benign odontogenic tumor, despite being locally invasive and associated with a risk of local recurrence.
A 47-year-old woman presented with a 2-year-old expansive bone lesion. Radiologically, a multilocular mass was identified in the left superior maxilla, compatible with a tumor of odontogenic origin. She was submitted to an extended resection, and the histology was consistent with a DGCT.
Central DGCT affects mainly male patients between the fourth and sixth decades, with a predilection for the posterior portion of the jaws. The symptoms are unspecific, and a vast percentage of patients is asymptomatic. Radiographically a unilocular feature is commonly found, unlike this case. The recommended treatment is extended local resection due to its high recurrence rate.
Due to its rarity, knowledge of this entity is necessary for a better diagnostic and therapeutic guidance.
牙源性影细胞肿瘤(DGCT)是一种文献报道约60例的疾病实体。它是一种良性牙源性肿瘤,尽管具有局部侵袭性且有局部复发风险。
一名47岁女性出现一个2年的膨胀性骨病变。影像学上,在上颌骨左侧发现一个多房性肿物,符合牙源性肿瘤。她接受了扩大切除术,组织学检查结果与DGCT一致。
中央型DGCT主要影响40至60岁的男性患者,好发于颌骨后部。症状不具特异性,很大比例的患者无症状。与本病例不同,影像学上通常表现为单房性特征。由于其高复发率,推荐的治疗方法是扩大局部切除术。
由于其罕见性,了解该疾病实体对于更好的诊断和治疗指导很有必要。