Luo Jianghui, Zhang Xudong, Tan Xiaohong, Chen Jiazun, Tang Miaomiao
Department of Anesthesiology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Medicine (Baltimore). 2025 Jul 18;104(29):e43256. doi: 10.1097/MD.0000000000043256.
The stellate ganglion block (SGB) is an extensively utilized regional anesthesia technique, integral to pain management protocols and postoperative analgesia. Its fundamental objective lies in the modulation of sympathetic nervous system activity, thereby facilitating the intricate balance of the autonomic, circulatory, endocrine, and immune systems to preserve homeostatic equilibrium. Postoperative sleep disorders (PSD), characterized by disruptions in sleep quantity and quality subsequent to surgical intervention, manifest as oscillations in the sleep-wake cycle and are indicative of postoperative neurocognitive impairments. Emerging research underscores the efficacy of SGB in mitigating PSD incidence through the targeted regulation of sympathetic ganglionic excitability and the modulation of endocrine and autonomic nervous system functions. This study offers an exhaustive appraisal of the effects of SGB on PSD, delving into the anatomical foundations of the procedure, elucidating its physiological mechanisms, and amalgamating pivotal insights derived from recent scholarly research.
星状神经节阻滞(SGB)是一种广泛应用的区域麻醉技术,是疼痛管理方案和术后镇痛不可或缺的一部分。其根本目标在于调节交感神经系统活动,从而促进自主、循环、内分泌和免疫系统的复杂平衡,以维持体内平衡。术后睡眠障碍(PSD)表现为手术干预后睡眠数量和质量的中断,表现为睡眠-觉醒周期的波动,是术后神经认知障碍的指标。新出现的研究强调了SGB通过有针对性地调节交感神经节兴奋性以及调节内分泌和自主神经系统功能来降低PSD发生率的功效。本研究对SGB对PSD的影响进行了详尽评估,深入探讨了该手术的解剖学基础,阐明了其生理机制,并融合了近期学术研究所获得的关键见解。