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原发性髂骨结核:一例报告

Primary iliac bone tuberculosis: a case report.

作者信息

Dahou Hajar, Saley Younoussa Fataou, Aragon Imane, El Aouadi Salma, El Harras Yahya, Benaissa Elmostafa, Ben Lahlou Yassine, Bahadi Abdelaali, El Fenni Jamal, Maleb Adil, Chadli Mariama, Elouennass Mostafa

机构信息

Department of Clinical Bacteriology, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco.

Nephrology Departement, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco.

出版信息

Access Microbiol. 2025 May 7;7(5). doi: 10.1099/acmi.0.000844.v3. eCollection 2025.

Abstract

Tuberculosis (TB) remains one of the world's leading causes of morbidity and mortality. It occurs in both pulmonary and extra-pulmonary forms. Primary iliac bone TB remains a rare clinical entity, even in endemic areas. The diagnosis of the disease can be challenging due to its similarity to other bone diseases. We report a rare case of primary iliac bone TB in a 63-year-old patient who was on peritoneal dialysis and had a medical history of hypertension and type II diabetes, which was complicated by diabetic retinopathy and diabetic kidney disease. Magnetic resonance imaging revealed osteomyelitis in the iliac bone, while real-time polymerase chain reaction using the GeneXpert system on a gluteal collection sample confirmed the diagnosis of TB. The integration of advanced molecular tools, such as GeneXpert, represents significant progress, enabling rapid and accurate diagnosis of TB and facilitating early initiation of treatment.

摘要

结核病(TB)仍然是全球发病和死亡的主要原因之一。它有肺内和肺外两种形式。原发性髂骨结核即使在流行地区仍然是一种罕见的临床病症。由于该疾病与其他骨病相似,其诊断可能具有挑战性。我们报告了一例罕见的原发性髂骨结核病例,患者为一名63岁接受腹膜透析的患者,有高血压和II型糖尿病病史,并伴有糖尿病视网膜病变和糖尿病肾病并发症。磁共振成像显示髂骨骨髓炎,而使用GeneXpert系统对臀部分泌物样本进行实时聚合酶链反应确诊为结核病。诸如GeneXpert等先进分子工具的整合代表了重大进展,能够快速准确地诊断结核病并促进早期治疗的开始。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0d/12281756/cb4089b5c88a/acmi-7-00844-g001.jpg

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