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健康儿童的总呼吸阻抗

Total respiratory impedance in healthy children.

作者信息

Hantos Z, Daróczy B, Gyurkovits K

出版信息

Pediatr Pulmonol. 1985 Mar-Apr;1(2):91-8. doi: 10.1002/ppul.1950010207.

DOI:10.1002/ppul.1950010207
PMID:4069798
Abstract

Impedance of the total respiratory system was measured in 121 healthy children aged 4-16 years during spontaneous breathing by pseudo-random forced oscillations between 3 and 10 Hz. Total respiratory resistance (Rrs), inertance (Irs) and compliance (Crs) were determined by least-mean-squares fitting. Estimates for inertance were reliable only for the larger children, where the values of Irs (0.0127 +/- 0.0034 SD) were similar to those reported for normal adults. Rrs correlated significantly (P less than 0.001) with height (r = -0.868), age (r = -0.865), and, in a subpopulation of the 6- to 16-year-old children, with forced vital capacity (r = -0.803). The corresponding correlation coefficients for Crs were 0.873, 0.844, and 0.853, respectively. Crs amounted to about a third of the static total compliance values of Sharp et al. (J Appl Physiol 1970; 29: 775-779) over the same interval of heights. In these relationships no significant difference was found between boys and girls.

摘要

通过在3至10Hz之间的伪随机强迫振荡,对121名4至16岁健康儿童在自主呼吸时的全呼吸系统阻抗进行了测量。通过最小二乘法拟合确定了全呼吸阻力(Rrs)、惯性(Irs)和顺应性(Crs)。只有年龄较大的儿童惯性估计值才可靠,其Irs值(0.0127±0.0034标准差)与正常成年人报告的数值相似。Rrs与身高(r = -0.868)、年龄(r = -0.865)以及在6至16岁儿童亚组中与用力肺活量(r = -0.803)显著相关(P < 0.001)。Crs的相应相关系数分别为0.873、0.844和0.853。在相同身高区间内,Crs约为Sharp等人(《应用生理学杂志》1970年;29:775 - 779)静态全顺应性值的三分之一。在这些关系中,未发现男孩和女孩之间存在显著差异。

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