Liu Shuang, Cheng Linqi, Li Sen
The Reproductive Laboratory, Shenyang, People's Republic of China.
Department of Biotechnology, Shenyang Medical College, Shenyang, People's Republic of China.
Int J Womens Health. 2025 Jul 18;17:2165-2174. doi: 10.2147/IJWH.S522708. eCollection 2025.
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder that has garnered attention in recent years for its intricate relationship with gut microbiota, which plays a significant role in the metabolic abnormalities associated with this condition. This review focuses on the characteristics of gut microbiota in polycystic ovary syndrome (PCOS). By analyzing current literature, we will focus on the alterations in gut microbiota composition, influential factors, and the pathophysiological mechanisms linking gut microbiota and PCOS, diagnostic approaches, therapeutic strategies, as well as controversies and future directions in this field are discussed. Understanding these relationships may provide insights into the disease mechanism and highlight novel treatment strategies for managing PCOS.
多囊卵巢综合征（PCOS）是一种常见的内分泌紊乱疾病，近年来因其与肠道微生物群的复杂关系而备受关注，肠道微生物群在与该病症相关的代谢异常中起着重要作用。本综述聚焦于多囊卵巢综合征（PCOS）中肠道微生物群的特征。通过分析当前文献，我们将关注肠道微生物群组成的改变、影响因素，以及连接肠道微生物群与PCOS的病理生理机制，讨论该领域的诊断方法、治疗策略以及争议和未来方向。了解这些关系可能有助于深入了解疾病机制，并突出管理PCOS的新治疗策略。
