Allagbé Ingrid, Zeller Marianne, Thomas Daniel, Airagnes Guillaume, Limosin Frédéric, Boussadi Abdelali, Chagué Frédéric, Le Faou Anne-Laurence
Physiopathology and Epidemiology Cerebro-Cardiovascular, PEC2, EA 7460 UFR Health Sciences, University of Burgundy and Franche Comté, Dijon, France.
Scientific Interest Group of the French Network of Excellence for Research on Tobacco, Nicotine and Related Products (GIS REfer Tab), Paris, France.
CJC Open. 2025 Feb 10;7(7):986-996. doi: 10.1016/j.cjco.2025.02.002. eCollection 2025 Jul.
In smokers with coronary artery diseases (CADs), smoking cessation (SC) is a major prevention goal. From the French national database of SC services (SCSs), CDTnet, we aimed to describe the social, medical, and smoking characteristics of smokers with CAD, as well as factors associated with their SC, according to sex.
A retrospective study was conducted of smokers with CAD included in the CDTnet from January 2001 to December 2018. Endpoints were abstinence and reduction of daily cigarette consumption. Abstinence was defined as SC maintained for ≥ 28 consecutive days, confirmed by a carbon monoxide measure in exhaled breath testing < 10 parties per million, and reduction was defined as at least a halving of consumption compared to consumption at the time of the first consultation. Sex stratification was performed.
Among 4532 smokers included, 21% were women, and their mean age was 55 years in both sexes. Nearly half smoked ≥ 20 cigarettes daily, and most (80%) received nicotine replacement therapy. The 28-day abstinence rate (54%) and reduction rate (24%) were similar in both sexes. Factors positively associated with SC in women were having made ≥ 1 previous quit attempt, and dual use of conventional and electronic cigarettes at the time of the first consultation. In men, being employed, being overweight or obese, being confident in quitting, and being prescribed nicotine replacement therapy at the first consultation were factors associated with success. Other cardiovascular and respiratory diseases were associated negatively with SC in both sexes.
Abstinence rates were similar for both sexes, with different factors associated with quit attempt results, according to sex, highlighting the need for tailored interventions that address the specific needs of men and women who intend to quit.
在患有冠状动脉疾病（CAD）的吸烟者中，戒烟是主要的预防目标。我们旨在根据法国国家戒烟服务（SCS）数据库CDTnet，描述患有CAD的吸烟者的社会、医学和吸烟特征，以及与他们戒烟相关的因素。
对2001年1月至2018年12月纳入CDTnet的患有CAD的吸烟者进行回顾性研究。终点指标为戒烟和每日吸烟量减少。戒烟定义为连续≥28天保持戒烟状态，通过呼出气体检测中一氧化碳含量<10 ppm确认，吸烟量减少定义为与首次咨询时的吸烟量相比至少减半。进行了性别分层。
在纳入的4532名吸烟者中，21%为女性，男女平均年龄均为55岁。近一半的人每天吸烟≥20支，大多数（80%）接受尼古丁替代疗法。男女的28天戒烟率（54%）和吸烟量减少率（24%）相似。与女性戒烟呈正相关的因素是之前曾≥1次尝试戒烟，以及首次咨询时同时使用传统香烟和电子烟。在男性中，就业、超重或肥胖、对戒烟有信心以及首次咨询时被开具尼古丁替代疗法是与成功戒烟相关的因素。其他心血管和呼吸系统疾病在男女中均与戒烟呈负相关。
男女戒烟率相似，但根据性别，与戒烟尝试结果相关的因素不同，这突出了需要针对有戒烟意愿的男性和女性的特定需求进行量身定制的干预措施。
