Csikós Nóra, Petro Bela, Gaál Zsófia Anna, Czigler István
Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Hungarian Research Network, Budapest, Hungary.
Department of Cognitive Science, Faculty of Natural Sciences, Budapest University of Technology and Economics, Budapest, Hungary.
Psychophysiology. 2025 Jul;62(7):e70111. doi: 10.1111/psyp.70111.
This study investigated the relationship between the pattern-specific event-related potential (ERP) components (C1, C2, C3) and the component specific to automatic change detection in the visual modality (visual mismatch response, vMMR) and the influence of stimulus placement on the latter. These insights would help to understand whether the emergence of vMMR is due to the modulation of exogenous activity or a specific deviant-related activity and advance the methodology of investigating vMMR. In two experiments, we presented checkerboard patterns in passive oddball sequences consisting of frequent (standard) and rare (deviant) events to examine vMMR as a function of the stimulated half-fields. In Experiment 1, the lower and upper half-field stimuli were presented within the same sequences, whereas in Experiment 2, they were presented in different sequences, completed with whole-field stimulation. As expected, we observed polarity reversal of the C1 and C2 components as a function of the stimulated half-field. Deviant stimuli elicited negative vMMR during lower and whole-field stimulation, but upper half-field stimulation evoked no significant vMMR. At lower half-field stimulation, the C2 component was larger to deviant stimuli, indicating the contribution of exogenous components to the deviant-standard difference. The sLORETA calculations showed that similar sources, including the primary visual cortex and other visual areas, were active during all exogenous and deviant-related components. Altogether, these results demonstrate the relationship between the pattern-specific and vMMR components and the more dominant influence of lower half-field stimulation in the recorded brain activity during automatic change detection.
本研究调查了特定模式的事件相关电位（ERP）成分（C1、C2、C3）与视觉模态中自动变化检测的特定成分（视觉失配反应，vMMR）之间的关系，以及刺激位置对后者的影响。这些见解将有助于理解vMMR的出现是由于外源性活动的调制还是特定的偏差相关活动，并推进研究vMMR的方法。在两个实验中，我们在由频繁（标准）和罕见（偏差）事件组成的被动oddball序列中呈现棋盘图案，以检查vMMR作为受刺激半视野的函数。在实验1中，下半视野和上半视野刺激在相同序列中呈现，而在实验2中，它们在不同序列中呈现，并辅以全视野刺激。正如预期的那样，我们观察到C1和C2成分的极性反转是受刺激半视野的函数。偏差刺激在下部和全视野刺激期间引发负vMMR，但上半视野刺激未引发显著的vMMR。在下部半视野刺激时，C2成分对偏差刺激更大，表明外源性成分对偏差-标准差异的贡献。sLORETA计算表明，包括初级视觉皮层和其他视觉区域在内的相似来源在所有外源性和偏差相关成分期间均活跃。总之，这些结果证明了特定模式和vMMR成分之间的关系，以及在自动变化检测期间下部半视野刺激在记录的大脑活动中更占主导地位的影响。
